Recombinant Human IDH3A Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | IDH3A-2376H |
Product Overview : | IDH3A MS Standard C13 and N15-labeled recombinant protein (NP_005521) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 39.6 kDa |
AA Sequence : | MAGPAWISKVSRLLGAFHNPKQVTR GFTGGVQTVTLIPGDGIGPEISAAV MKIFDAAKAPIQWEERNVTAIQGPG GKWMIPSEAKESMDKNKMGLKGPLK TPIAAGHPSMNLLLRKTFDLYANVR PCVSIEGYKTPYTDVNIVTIRENTE GEYSGIEHVIVDGVVQSIKLITEGA SKRIAEFAFEYARNNHRSNVTAVHK ANIMRMSDGLFLQKCREVAESCKDI KFNEMYLDTVCLNMVQDPSQFDVLV MPNLYGDILSDLCAGLIGGLGVTPS GNIGANGVAIFESVHGTAPDIAGKD MANPTALLLSAVMMLRHMGLFDHAA RIEAACFATIKDGKSLTKDLGGNAK CSDFTEEICRRVKDLDTRTRPLEQK LISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha [ Homo sapiens (human) ] |
Official Symbol : | IDH3A |
Synonyms : | IDH3A; isocitrate dehydrogenase 3 (NAD+) alpha; isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial; H IDH alpha; isocitrate dehydrogenase (NAD+) alpha chain; isocitrate dehydrogenase [NAD] subunit alpha; mitochondrial; isocitric dehydrogenase; NAD(H) specific isocitrate dehydrogenase alpha subunit; NAD+ specific ICDH; H-IDH alpha; NAD+-specific ICDH; NAD(+)-specific ICDH subunit alpha; isocitric dehydrogenase subunit alpha; NAD(H)-specific isocitrate dehydrogenase alpha subunit; |
Gene ID : | 3419 |
mRNA Refseq : | NM_005530 |
Protein Refseq : | NP_005521 |
MIM : | 601149 |
UniProt ID : | P50213 |
Products Types
◆ Recombinant Protein | ||
IDH3A-4411M | Recombinant Mouse IDH3A Protein, His (Fc)-Avi-tagged | +Inquiry |
IDH3A-1136H | Recombinant Human IDH3A Protein, His (Fc)-Avi-tagged | +Inquiry |
Idh3a-3473M | Recombinant Mouse Idh3a Protein, Myc/DDK-tagged | +Inquiry |
IDH3A-2642R | Recombinant Rat IDH3A Protein, His (Fc)-Avi-tagged | +Inquiry |
IDH3A-2014R | Recombinant Rhesus Macaque IDH3A Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IDH3A-5305HCL | Recombinant Human IDH3A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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