Recombinant Human IFIH1 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | IFIH1-2162H |
Product Overview : | IFIH1 MS Standard C13 and N15-labeled recombinant protein (NP_071451) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-dependent type 19. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 116.5 kDa |
AA Sequence : | MSNGYSTDENFRYLISCFRARVKMY IQVEPVLDYLTFLPAEVKEQIQRTV ATSGNMQAVELLLSTLEKGVWHLGW TREFVEALRRTGSPLAARYMNPELT DLPSPSFENAHDEYLQLLNLLQPTL VDKLLVRDVLDKCMEEELLTIEDRN RIAAAENNGNESGVRELLKRIVQKE NWFSAFLNVLRQTGNNELVQELTGS DCSESNAEIENLSQVDGPQVEEQLL STTVQPNLEKEVWGMENNSSESSFA DSSVVSESDTSLAEGSVSCLDESLG HNSNMGSDSGTMGSDSDEENVAARA SPEPELQLRPYQMEVAQPALEGKNI IICLPTGSGKTRVAVYIAKDHLDKK KKASEPGKVIVLVNKVLLVEQLFRK EFQPFLKKWYRVIGLSGDTQLKISF PEVVKSCDIIISTAQILENSLLNLE NGEDAGVQLSDFSLIIIDECHHTNK EAVYNNIMRHYLMQKLKNNRLKKEN KPVIPLPQILGLTASPGVGGATKQA KAEEHILKLCANLDAFTIKTVKENL DQLKNQIQEPCKKFAIADATREDPF KEKLLEIMTRIQTYCQMSPMSDFGT QPYEQWAIQMEKKAAKEGNRKERVC AEHLRKYNEALQINDTIRMIDAYTH LETFYNEEKDKKFAVIEDDSDEGGD DEYCDGDEDEDDLKKPLKLDETDRF LMTLFFENNKMLKRLAENPEYENEK LTKLRNTIMEQYTRTEESARGIIFT KTRQSAYALSQWITENEKFAEVGVK AHHLIGAGHSSEFKPMTQNEQKEVI SKFRTGKINLLIATTVAEEGLDIKE CNIVIRYGLVTNEIAMVQARGRARA DESTYVLVAHSGSGVIERETVNDFR EKMMYKAIHCVQNMKPEEYAHKILE LQMQSIMEKKMKTKRNIAKHYKNNL SLITFLCKNCSVLACSGEDIHVIEK MHHVNMTPEFKELYIVRENKTLQKK CADYQINGEIICKCGQAWGTMMVHK GLDLPCLKIRNFVVVFKNNSTKKQY KKWVELPITFPNLDYSECCLFSDED TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | IFIH1 interferon induced with helicase C domain 1 [ Homo sapiens (human) ] |
Official Symbol : | IFIH1 |
Synonyms : | IFIH1; interferon induced with helicase C domain 1; interferon-induced helicase C domain-containing protein 1; helicard; Hlcd; IDDM19; MDA 5; MDA5; CADM-140 autoantigen; helicase with 2 CARD domains; RNA helicase-DEAD box protein 116; murabutide down-regulated protein; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; melanoma differentiation associated protein-5; melanoma differentiation-associated protein 5; interferon-induced with helicase C domain protein 1; clinically amyopathic dermatomyositis autoantigen 140 kDa; MDA-5; MGC133047; |
Gene ID : | 64135 |
mRNA Refseq : | NM_022168 |
Protein Refseq : | NP_071451 |
MIM : | 606951 |
UniProt ID : | Q9BYX4 |
Products Types
◆ Recombinant Protein | ||
IFIH1-1252H | Recombinant Human IFIH1 Protein, His-tagged | +Inquiry |
Ifih1-3479M | Recombinant Mouse Ifih1 Protein, Myc/DDK-tagged | +Inquiry |
IFIH1-3H | Recombinant Human IFIH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
IFIH1-4431M | Recombinant Mouse IFIH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
IFIH1-2022R | Recombinant Rhesus Macaque IFIH1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IFIH1-5289HCL | Recombinant Human IFIH1 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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