Recombinant Human IFITM5 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: IFITM5-726H
• Product Overview: IFITM5 MS Standard C13 and N15-labeled recombinant protein (NP_001020466) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a membrane protein thought to play a role in bone mineralization. This gene is located on chromosome 11 in a cluster of related genes which are induced by interferon, however, this gene has not been shown to be interferon inducible. A similar gene, located in a gene cluster on mouse chromosome 7, is a member of the interferon-inducible fragilis gene family. The mouse gene encodes a transmembrane protein described as participating in germ cell competence. A mutation in the 5' UTR of this gene has been associated with osteogenesis imperfecta type V (PMID: 22863190, 22863195).
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 14.2 kDa
• AA Sequence: MDTAYPREDTRAPTPSKAGAHTALT LGAPHPPPRDHLIWSVFSTLYLNLC CLGFLALAYSIKARDQKVVGDLEAA RRFGSKAKCYNILAAMWTLVPPLLL LGLVVTGALHLARLAKDSAAFFSTK FDDADYDTRTRPLEQKLISEEDLAA NDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: IFITM5 interferon induced transmembrane protein 5 [ Homo sapiens (human) ]
• Official Symbol: IFITM5
• Synonyms: IFITM5; interferon induced transmembrane protein 5; interferon-induced transmembrane protein 5; BRIL; fragilis4; Hrmp1; bone-restricted interferon induced transmembrane protein-like protein; bone-restricted interferon-induced transmembrane protein-like protein
• Gene ID: 387733
• mRNA Refseq: NM_001025295
• Protein Refseq: NP_001020466
• MIM: 614757
• UniProt ID: A6NNB3