Recombinant Human IFNA1 Protein, His&GST-tagged

• Cat.No.: IFNA1-1647H
• Product Overview: Recombinant Human IFNA1 Protein (Cys24-Leu181) with N-His&GST tag was expressed in E. coli.

Specification

• Description: This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. This cytokine is upregulated in preeclamptic placentas and is thought to be a mediator of preeclampsia.
• Source: E. coli
• Species: Human
• Tag: N-His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 48.2 kDa
  Accurate Molecular Mass: 48 kDa
• Protein length: Cys24-Leu181
• Purity: > 90%
• Applications: Cell culture; Activity Assays.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

Gene Information

• Gene Name: IFNA1 interferon alpha 1 [ Homo sapiens (human) ]
• Official Symbol: IFNA1
• Synonyms: IFNA1; interferon alpha 1; IFL; IFN; IFNA@; IFNA13; leIF D; IFN-ALPHA; IFN-alphaD; interferon alpha-1/13; IFN-alpha-1/13; interferon alpha 1b; interferon alpha-D; interferon-alpha1
• Gene ID: 3439
• mRNA Refseq: NM_024013
• Protein Refseq: NP_076918
• MIM: 147660
• UniProt ID: P01562