Recombinant Human IFNB1 protein(Met1-Asn187), hFc-tagged
Cat.No. : | IFNB1-14H |
Product Overview : | Recombinant Human IFNβ (NP_002167.1) (Met 1-Asn 187) was expressed in HEK293, fused with the Fc region of Human IgG1 at the C-terminus. |
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Source : | HEK293 |
Species : | Human |
Tag : | C-hFc |
Protein length : | Met1-Asn187 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | Measured in antiviral assays using WISH human amnion cells infected with vesicular stomatitis virus (VSV). The ED50 for this effect is 0.08-0.8 ng/mL. |
Molecular Mass : | The recombinant human IFNβ/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 404 amino acids and has a predicted molecular mass of 46.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh IFNβ/Fc monomer is approximately 52 kDa due to glycosylation. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 95 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | IFNB1 interferon, beta 1, fibroblast [ Homo sapiens ] |
Official Symbol : | IFNB1 |
Synonyms : | IFNB1; interferon, beta 1, fibroblast; IFNB; interferon beta; IFB; IFF; IFN-beta; fibroblast interferon; MGC96956; |
Gene ID : | 3456 |
mRNA Refseq : | NM_002176 |
Protein Refseq : | NP_002167 |
MIM : | 147640 |
UniProt ID : | P01574 |
Products Types
◆ Lysates | ||
IFNB1-2931HCL | Recombinant Human IFNB1 cell lysate | +Inquiry |
IFNB1-1117MCL | Recombinant Mouse IFNB1 cell lysate | +Inquiry |
IFNB1-001HCL | Recombinant Human IFNB1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionIFNB1 is generally not recommended for individuals with a history of hypersensitivity to interferons or other components of the drug. It should be used with caution in patients with certain pre-existing medical conditions.
IFNB1 is being investigated for its potential role in cancer treatment due to its immunomodulatory effects. Clinical trials are ongoing to evaluate its efficacy in various types of cancer.
Common side effects include flu-like symptoms, injection site reactions, and changes in blood cell counts. Serious side effects are rare but can include liver problems and allergic reactions.
IFNB1 is often administered through subcutaneous or intramuscular injections. The frequency and dosage depend on the specific condition being treated.
IFNB1 is also used in the treatment of certain viral infections, such as hepatitis B and C. It has antiviral properties that can inhibit viral replication.
Customer Reviews (3)
Write a reviewThe manufacturer not only ensures the provision of superior protein but also aids researchers with their solid technical support, offering the necessary resources to optimize experimental protocols.
the IFNB1 protein offers numerous advantages for researchers conducting trials due to its high quality and stability.
manufacturers or suppliers of proteins can play a crucial role in supporting researchers during trials.
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