Recombinant Human IFNGR1 Protein, His-tagged
Cat.No. : | IFNGR1-001H |
Product Overview : | Recombinant human IFNGR1(18-245aa), fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
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Description : | IFNGR1, also known as interferon gamma receptor 1, is a member of the hematopoietic cytokine receptor superfamily. It is a receptor that binds interferon-γ, the sole member of interferon type II. It induces the rapid dimerization of chains, thereby forming a site that is recognized by the extracellular domain of IFNGR2. It is expressed in a membrane-bound form in many cell types, and is over-expressed in tumour cells. Its signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6. It is crucial for host defence against mycobacterial infections. It is associated with susceptibility to pulmonary tuberculosis (TB). |
Source : | Insect cell |
Species : | Human |
Tag : | His |
Form : | Liquid |
Molecular Mass : | 26.6 kDa |
AASequence : | EMGTADLGPSSVPTPTNVTIESYNM NPIVYWEYQIMPQVPVFTVEVKNYG VKNSEWIDACINISHHYCNISDHVG DPSNSLWVRVKARVGQKESAYAKSE EFAVCRDGKIGPPKLDIRKEEKQIM IDIFHPSVFVNGDEQEVDYDPETTC YIRVYNVYVRMNGSEIQYKILTQKE DDCDEIQCQLAIPVSSLNSQYCVSA EGVLHVWGVTTEKSKEVCITIFNSS IKGHHHHHH |
N-terminal Sequence Analysis : | Glu 18 |
Endotoxin : | < 1.0 EU per 1 μg of protein (determined by LAL method) |
Purity : | > 90% by SDS - PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1.0 mg/mL (determined by Absorbance at 280nm) |
Storage Buffer : | In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
Warning : | For research use only. This product is not intended or approved for human, diagnostics or veterin |
Gene Name : | IFNGR1 interferon gamma receptor 1 [ Homo sapiens (human) ] |
Official Symbol : | IFNGR1 |
Synonyms : | IFNGR1; interferon gamma receptor 1; CD119; IFNGR; IMD27A; IMD27B; |
Gene ID : | 3459 |
mRNA Refseq : | NM_000416 |
Protein Refseq : | NP_000407 |
MIM : | 107470 |
UniProt ID : | P15260 |
Products Types
◆ Recombinant Protein | ||
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Ifngr1-6954M | Active Recombinant Mouse Ifngr1 protein(Met1-Asp253), His-tagged | +Inquiry |
IFNGR1-062H | Recombinant Human IFNGR1 Protein, C-His-tagged | +Inquiry |
Ifngr1-1218M | Recombinant Mouse Ifngr1 Protein, MYC/DDK-tagged | +Inquiry |
IFNGR1-297H | Recombinant Human IFNGR1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
IFNGR1-1775MCL | Recombinant Mouse IFNGR1 cell lysate | +Inquiry |
IFNGR1-1003CCL | Recombinant Cynomolgus IFNGR1 cell lysate | +Inquiry |
IFNGR1-2646HCL | Recombinant Human IFNGR1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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