Recombinant Human IGFALS Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: IGFALS-3934H
• Product Overview: IGFALS MS Standard C13 and N15-labeled recombinant protein (NP_004961) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 66.1 kDa
• AA Sequence: MALRKGGLALALLLLSWVALGPRSL EGADPGTPGEAEGPACPAACVCSYD DDADELSVFCSSRNLTRLPDGVPGG TQALWLDGNNLSSVPPAAFQNLSSL GFLNLQGGQLGSLEPQALLGLENLC HLHLERNQLRSLALGTFAHTPALAS LGLSNNRLSRLEDGLFEGLGSLWDL NLGWNSLAVLPDAAFRGLGSLRELV LAGNRLAYLQPALFSGLAELRELDL SRNALRAIKANVFVQLPRLQKLYLD RNLIAAVAPGAFLGLKALRWLDLSH NRVAGLLEDTFPGLLGLRVLRLSHN AIASLRPRTFKDLHFLEELQLGHNR IRQLAERSFEGLGQLEVLTLDHNQL QEVKAGAFLGLTNMAVMNLSGNCLR NLPEQVFRGLGKLHSLHLEGSCLGR IRPHTFTGLSGLRRLFLKDNGLVGI EEQSLWGLAELLELDLTSNQLTHLP HRLFQGLGKLEYLLLSRNRLAELPA DALGPLQRAFWLDVSHNRLEALPNS LLAPLGRLRYLSLRNNSLRTFTPQP PGLERLWLEGNPWDCGCPLKALRDF ALQNPSAVPRFVQAICEGDDCQPPA YTYNNITCASPPEVVGLDLRDLSEA HFAPCTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: IGFALS insulin like growth factor binding protein acid labile subunit [ Homo sapiens (human) ]
• Official Symbol: IGFALS
• Synonyms: IGFALS; insulin-like growth factor binding protein, acid labile subunit; insulin-like growth factor-binding protein complex acid labile subunit; ALS; insulin-like growth factor binding protein complex acid labile chain
• Gene ID: 3483
• mRNA Refseq: NM_004970
• Protein Refseq: NP_004961
• MIM: 601489
• UniProt ID: P35858