Recombinant Human IGFBP7 protein

• Cat.No.: IGFBP7-55H
• Product Overview: Recombinant Human IGFBP7 protein was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: N/A
• Form: Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM Tris-HCl, pH 8.6, 150 mM NaCl.
• Molecular Mass: Approximately 26.4 kDa, a single non-glycosylated polypeptide chain containing 256 amino acids.
• AASequence: SSSDTCGPCE PASCPPLPPL GCLLGETRDA CGCCPMCARG EGEPCGGGGA GRGYCAPGME CVKSRKRRKG KAGAAAGGPG VSGVCVCKSR YPVCGSDGTT YPSGCQLRAA SQRAESRGEK AITQVSKGTC EQGPSIVTPP KDIWNVTGAQ VYLSCEVIGI PTPVLIWNKV KRGHYGVQRT ELLPGDRDNL AIQTRGGPEK HEVTGWVLVS PLSKEDAGEY ECHASNSQGQ ASASAKITVV DALHEIPVKK GEGAEL
• Endotoxin: Less than 0.1 EU/μg of rHuIGF-BP7 as determined by LAL method.
• Purity: > 95 % by SDS-PAGE and HPLC analyses.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  - 12 months from date of receipt, -20 to -70 °C as supplied.
  - 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  - 3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C.

Gene Information

• Gene Name: IGFBP7 insulin-like growth factor binding protein 7 [ Homo sapiens ]
• Official Symbol: IGFBP7
• Synonyms: IGFBP7; insulin-like growth factor binding protein 7; insulin-like growth factor-binding protein 7; FSTL2; IGFBP 7; MAC25; PSF; IGFBP-rP1; angiomodulin; IGF-binding protein 7; PGI2-stimulating factor; tumor-derived adhesion factor; prostacyclin-stimulating factor; AGM; TAF; IBP-7; IGFBP-7; RAMSVPS; IGFBP-7v; IGFBPRP1
• Gene ID: 3490
• mRNA Refseq: NM_001253835
• Protein Refseq: NP_001240764
• MIM: 602867
• UniProt ID: Q16270

Reviews

04/09/2017

Its purity and stability ensure consistent and accurate results, making it an ideal tool for my research endeavors.

11/02/2016

The manufacturer's commitment to maintaining stringent quality control measures guarantees that I can trust the protein's integrity and reliability throughout my experiments.

09/19/2016

This partnership enhances research productivity while ensuring accurate and meaningful outcomes.

Q&As

In what types of cancer is IGFBP7 research particularly focused?

Research on IGFBP7 is often concentrated in breast, lung, prostate, and colorectal cancers, among others.

How does IGFBP7 contribute to cardiovascular health?

IGFBP7 has been associated with cardiovascular health, and its potential role in protecting against cardiovascular diseases is an area of ongoing research.

Can IGFBP7 be used in therapeutic interventions?

The potential therapeutic applications of IGFBP7 are being explored, including its use in targeted cancer therapies and other medical interventions.

Can IGFBP7 serve as a biomarker for cancer detection?

Some studies suggest that IGFBP7 levels in blood or tissues may have potential as a biomarker for cancer detection.

How does IGFBP7 affect cell cycle regulation?

IGFBP7 has been shown to influence the cell cycle by promoting cell cycle arrest, which can be crucial in preventing uncontrolled cell growth.