| Description : |
This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
27 kDa |
| Protein Length : |
282 |
| AA Sequence : |
MERPSLRALLLGAAGLLLLLLPLSS SSSSDTCGPCEPASCPPLPPLGCLL GETRDACGCCPMCARGEGEPCGGGG AGRGYCAPGMECVKSRKRRKGKAGA AAGGPGVSGVCVCKSRYPVCGSDGT TYPSGCQLRAASQRAESRGEKAITQ VSKGTCEQGPSIVTPPKDIWNVTGA QVYLSCEVIGIPTPVLIWNKVKRGH YGVQRTELLPGDRDNLAIQTRGGPE KHEVTGWVLVSPLSKEDAGEYECHA SNSQGQASASAKITVVDALHEIPVK KGEGAEL |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
