Recombinant Human ILF3 293 Cell Lysate

• Cat.No.: ILF3-5221HCL

Specification

• Description: Antigen standard for interleukin enhancer binding factor 3, 90kDa (ILF3), transcript variant 1 is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection.
• Source: HEK 293 cells
• Species: Human
• Components: This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol).
• Size: 0.1 mg
• Storage Instruction: Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment.
• Applications: ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane.

Gene Information

• Gene Name: ILF3 interleukin enhancer binding factor 3, 90kDa [ Homo sapiens ]
• Official Symbol: ILF3
• Synonyms: ILF3; interleukin enhancer binding factor 3, 90kDa; interleukin enhancer binding factor 3, 90kD; interleukin enhancer-binding factor 3; DRBP76; M phase phosphoprotein 4; MPHOSPH4; MPP4; NF90; NFAR 1; M-phase phosphoprotein 4; translational control protein 80; dsRNA binding protein NFAR-2/MPP4; nuclear factor associated with dsRNA; double-stranded RNA-binding protein, 76 kD; nuclear factor of activated T-cells 90 kDa; nuclear factor of activated T-cells, 90 kD; CBTF; DRBF; MMP4; NFAR; NF110; NF90a; NF90b; NFAR2; TCP80; NF110b; NFAR-1; TCP110; NF-AT-90
• Gene ID: 3609
• mRNA Refseq: NM_001137673
• Protein Refseq: NP_001131145
• MIM: 603182
• UniProt ID: Q12906
• Chromosome Location: 19p13.2
• Function: DNA binding; RNA binding; double-stranded RNA binding; protein binding

Reviews

07/17/2022

The impurities are not obvious, clear and transparent, and the purity is high.

07/13/2022

It can meet the needs of daily experiments, and the expression effect is good.

02/27/2021

ILF3 has performed well in experiments and is a reliable choice.

Q&As

Which tumors are associated with ILF3? What role does it play in tumor development?

This is associated with a variety of tumors, including breast cancer, lung cancer, and colon cancer. In tumor development, ILF3 may promote cell proliferation, apoptosis inhibition, and metastasis.

What progress has been made in the exploration of new methods and new drugs for ILF3 treatment of tumors?

At present for ILF3 new treatment for cancer and new drug exploration is still in its infancy, but some ILF3 related drugs and treatment strategies are in development and evaluation, bring new hope for patients.

Is ILF3 associated with tumor microenvironment and immune escape?

This peotein may be associated with tumor microenvironment and immune escape, and can regulate the interaction between tumor cells and immune cells, further deepening our understanding of the mechanism of immune escape.

Is there a relationship between LF3 and tumor prognosis and treatment response?

The association between ILF3 and tumor prognosis and treatment response needs to be further studied, but according to the current study, high expression of ILF3 may be associated with poor prognosis and drug resistance in cancer patients.

What are the functions and mechanisms of ILF3 in infectious diseases?

ILF3 may play an important immunomodulatory function in infectious diseases and may be involved in the immune response and inflammatory response caused by viral or bacterial infection.

What is ILF3 role in autoimmune diseases? What autoimmune diseases might it be involved in?

It may play an important role in autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus (sle), may be involved in these diseases by means of immune regulation of occurrence and development.