Recombinant Human INF2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: INF2-3845H
• Product Overview: INF2 MS Standard C13 and N15-labeled recombinant protein (NP_071934) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene represents a member of the formin family of proteins. It is considered a diaphanous formin due to the presence of a diaphanous inhibitory domain located at the N-terminus of the encoded protein. Studies of a similar mouse protein indicate that the protein encoded by this locus may function in polymerization and depolymerization of actin filaments. Mutations at this locus have been associated with focal segmental glomerulosclerosis 5.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 135.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: INF2 inverted formin 2 [ Homo sapiens (human) ]
• Official Symbol: INF2
• Synonyms: INF2; inverted formin 2; FSGS5; CMTDIE; pp9484; C14orf151; C14orf173; inverted formin-2; HBEAG-binding protein 2 binding protein C; HBEBP2-binding protein C; inverted formin, FH2 and WH2 domain containing
• Gene ID: 64423
• mRNA Refseq: NM_022489
• Protein Refseq: NP_071934
• MIM: 610982
• UniProt ID: Q27J81

Reviews

01/29/2022

The product's cost-effectiveness and clear instructions were instrumental in our experimental design.

04/22/2021

Clear and concise instructions simplified the application of the product, reducing the learning curve.

02/02/2016

We appreciated the product’s efficiency in achieving target protein upregulation with minimal time investment.

Q&As

Can INF2 protein’s function affect cytoskeletal organization?

Yes, INF2 protein’s function modulates cytoskeletal organization, particularly actin filaments.

Does INF2 protein play a role in cell adhesion and migration?

Yes, INF2 protein’s role might involve regulating cell adhesion and migration processes.

How is INF2 protein’s impact on actin polymerization assessed?

Research employs techniques like live-cell imaging to study INF2 protein’s effects on actin polymerization.

Can INF2 protein’s role be linked to cellular responses to mechanical forces?

Yes, INF2 protein’s function may impact cellular responses to mechanical stresses and forces.

Is INF2 protein’s activity regulated by extracellular cues?

Yes, INF2 protein’s activity can be influenced by extracellular signals and environmental factors.

How is INF2 protein’s involvement studied in cell motility?

Research aims to understand how INF2 protein’s role contributes to cellular motility and migration.

How does INF2 protein contribute to membrane remodeling?

INF2 protein participates in membrane remodeling processes, shaping cellular membranes.