Recombinant Human INSC Protein, GST-tagged

• Cat.No.: INSC-5099H
• Product Overview: Human INSC full-length ORF ( AAI56333.1, 1 a.a. - 579 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: In Drosophila, neuroblasts divide asymmetrically into another neuroblast at the apical side and a smaller ganglion mother cell on the basal side. Cell polarization is precisely regulated by 2 apically localized multiprotein signaling complexes that are tethered by Inscuteable, which regulates their apical localization (Izaki et al., 2006 [PubMed 16458856]).[supplied by OMIM
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 63.7 kDa
• AA Sequence: MRRPPGNGEAASEGPGGWGLWGVQE SRRLCCAGHDRCKQALLQIGINMMA LPGGRHLDSVTLPGQRLHLMQVDSV QRWMEDLKLMTECECMCVLQAKPIS LEEDAQGDLILAGGPGPGDPLQLLL KRGWVISTELRRIGQKLAQDRWARV HSMSVRLTCHARSMVSEYSAVSRNS LKEMGEIEKLLMEKCSELSAVTERC LQVENEHVLKSMKACVSETLSMLGQ HFGQLLELALTREVQALVRKIDASD NIYTTESTTGNLFSLTQEGAPLCRI IAKEGGVVALFKVCRQDSFRCLYPQ ALRTLASICCVEEGVHQLEKVDGVL CLADILTDNSHSEATRAEAAAVVAQ VTSPHLPVTQHLSSFLESMEEIVTA LVKLCQEASSGEVFLLASAALANIT FFDTMACEMLLQLNAIRVLLEACSD KQRVDTPYTRDQIVTILANMSVLEQ CASDIIQENGVQLIMGMLSEKPRSG TPAEVAACERVQQKAAVTLARLSRD PDVAREAVRLSCMSRLIELCRSPSE RNSSDAVLVACLAALRRLAGVCPEG LQDSDFQQLVQPRLVDSFLLCSNME ESFV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: INSC inscuteable homolog (Drosophila) [ Homo sapiens ]
• Official Symbol: INSC
• Synonyms: INSC; inscuteable homolog (Drosophila); protein inscuteable homolog
• Gene ID: 387755
• mRNA Refseq: NM_001031853
• Protein Refseq: NP_001027024
• MIM: 610668
• UniProt ID: Q1MX18