Recombinant Human INSIG2 Protein, His-tagged, OVA Conjugated
Cat.No. : | INSIG2-2820H |
Product Overview : | OVA Conjugated Recombinant Human INSIG2 Protein (Met1-Pro16) fused with a N-His tag. |
- Specification
- Gene Information
- Related Products
- Download
Description : | The protein encoded by this gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi. |
Source : | Protein Conjugation |
Species : | Human |
Tag : | N-His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 16 kDa |
Protein length : | Met1-Pro16 |
Purity : | > 90% |
Applications : | Immunogen; SDS-PAGE; WB. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months. |
Storage Buffer : | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
Reconstitution : | Reconstitute in PBS or others. |
Gene Name : | INSIG2 insulin induced gene 2 [ Homo sapiens (human) ] |
Official Symbol : | INSIG2 |
Synonyms : | INSIG2; insulin induced gene 2; INSIG-2; insulin-induced gene 2 protein; INSIG2 membrane protein; insulin induced protein 2 |
Gene ID : | 51141 |
mRNA Refseq : | NM_016133 |
Protein Refseq : | NP_057217 |
MIM : | 608660 |
UniProt ID : | Q9Y5U4 |
Products Types
◆ Recombinant Protein | ||
INSIG2-1188H | Recombinant Human INSIG2 Protein, His (Fc)-Avi-tagged | +Inquiry |
INSIG2-2735R | Recombinant Rat INSIG2 Protein, His (Fc)-Avi-tagged | +Inquiry |
INSIG2-2100R | Recombinant Rhesus Macaque INSIG2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Insig2-3552M | Recombinant Mouse Insig2 Protein, Myc/DDK-tagged | +Inquiry |
INSIG2-5098H | Recombinant Human INSIG2 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
INSIG2-5192HCL | Recombinant Human INSIG2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (7)
Ask a questionWhile specific post-translational modifications may exist, the current literature provides limited information on post-translational regulation of INSIG2.
INSIG2 contributes to insulin sensitivity by regulating lipid metabolism and insulin signaling pathways.
INSIG2 inhibits the activity of both SREBP-1 and SREBP-2, impacting lipogenesis and cholesterol biosynthesis.
INSIG2 is a key regulator of cholesterol synthesis, modulating the activation of SREBP-2, a master regulator of cholesterol biosynthesis.
INSIG2 is involved in the cellular response to ER stress, playing a role in maintaining ER homeostasis.
There is evidence linking INSIG2 to cancer development, suggesting a potential role in tumorigenesis.
Yes, INSIG2 expression can vary in response to different dietary conditions, reflecting its role in metabolic adaptation.
Customer Reviews (3)
Write a reviewWe observed that results obtained with the product remained stable and reliable over long-term experiments.
The product's impact extended to data analysis, with intuitive tools for interpreting experimental results.
Its adaptability to various sample types and conditions made it a valuable asset for our diverse projects.
Ask a Question for All INSIG2 Products
Required fields are marked with *
My Review for All INSIG2 Products
Required fields are marked with *
Inquiry Basket