Recombinant Human Insulin-Like Growth Factor 1 Receptor
Cat.No. : | IGF1R-1631H |
- Specification
- Gene Information
- Related Products
Cat. No. : | IGF1R-1631H |
Description : | Insulin-like Growth Factor 1 (IGF-1) Receptor is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection.IGF-1 receptor may be a central regulator of mammalian lifespan2 and when activated, it results in survival and proliferation in mitosis-competent cells, and growth (hypertrophy) in tissues such as skeletal muscle and cardiac muscle. IGF1R is now an attractive anti-cancer treatment target. |
Source : | Mammalian cells |
State Of Matter : | Lyophilized. |
Purity : | >95% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Molecular Weight : | The predicted molecular weight of Recombinant Human IGF-I sR is Mr 81, 23, 104 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 150, 120, 48 kDa. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
Gene Name : | IGF1R insulin-like growth factor 1 receptor [ Homo sapiens ] |
Synonyms : | IGF1R; insulin-like growth factor 1 receptor; IGFR; CD221; IGFIR; JTK13; MGC18216; MGC142170; MGC142172; soluble IGF1R variant 1; soluble IGF1R variant 2; EC 2.7.10.1; CD221; IGF-I receptor; CD221 antigen; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain |
Gene ID : | 3480 |
mRNA Refseq : | NM_000875 |
Protein Refseq : | NP_000866 |
MIM : | 147370 |
UniProt ID : | P08069 |
Chromosome Location : | 15q26.3 |
Pathway : | Adherens junction; Colorectal cancer; Endocytosis; Focal adhesion; Glioma; Long-term depression; Melanoma; Pathways in cancer; Prostate cancer |
Function : | ATP binding; identical protein binding; insulin binding; insulin receptor binding; insulin receptor substrate binding; insulin-like growth factor I binding; insulin-like growth factor receptor activity; nucleotide binding; phosphoinositide 3-kinase binding; receptor activity; transferase activity |
Products Types
◆ Recombinant Protein | ||
IGF1R-299H | Recombinant Human IGF1R Protein, His and Strep-tagged | +Inquiry |
IGF1R-2660R | Recombinant Rat IGF1R Protein, His (Fc)-Avi-tagged | +Inquiry |
IGF1R-22M | Active Recombinant Mouse IGF1R Protein, His-tagged | +Inquiry |
IGF1R-0995H | Recombinant Human IGF1R Protein (S982-K1286), His tagged | +Inquiry |
IGF1R-1392H | Recombinant Human IGF1R Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
IGF1R-2928HCL | Recombinant Human IGF1R cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1601 | HEK 293 IGF1R Bioassay Kit | +Inquiry |
Kit-1600 | IGF1R Functional Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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