Recombinant Human Insulin-like Growth Factor Binding Protein 4
Cat.No. : | IGFBP4-614H |
Product Overview : | Recombinant humanIGFBP4 protein was expressed in E. coli. IGFBP4 inhibits the activity ofIGF-I and IGF-II by binding in a manner that results in the formation ofcomplexes with reduced ability to signal through cell surface IGF receptors. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IGFBP4-614H |
Description : | This gene is amember of the insulin-like growth factor binding protein (IGFBP) family andencodes a protein with an IGFBP domain and a thyroglobulin type-I domain. Theprotein binds both insulin-like growth factors (IGFs) I and II and circulatesin the plasma in both glycosylated and non-glycosylated forms. Binding ofthis protein prolongs the half-life of the IGFs and alters their interactionwith cell surface receptors. |
Source : | E. coli |
Species : | Human |
Form : | Lyophilized from asterile solution without additives. |
Purity : | >98.0% asdetermined by RP-HPLC and SDS-PAGE analyses. |
Molecular Weight : | 26.1 kDa |
Endotoxin Level : | <0.1 ng/μg ofprotein. |
Reconstitution : | Centrifuge vialprior to opening. Reconstituted in water to a concentration of 0.1-1.0 mg/ml.This solution can be diluted in water or other buffer solutions or stored at-20°C. |
Storage : | The lyophilizedprotein is stable for a few weeks at room temperature, but best stored at -20°C.Reconstituted human IGFBP4 should be stored in working aliquots at -20°C. Avoidrepeated freeze-thaw cycles. |
OfficialSymbol : | IGFBP4 |
Pathways : | Diabetes pathways; MyometrialRelaxation and Contraction Pathways; Regulation of Insulin-like Growth Factor(IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs); Wntsignaling network |
Gene Name : | IGFBP4 insulin-like growthfactor binding protein 4 [ Homo sapiens ] |
Synonyms : | IGFBP4; insulin-likegrowth factor binding protein 4; BP-4; IBP4; IGFBP-4; HT29-IGFBP; insulin-likegrowth factor-binding protein 4; IBP-4; OTTHUMP00000164451; IGF-bindingprotein 4; Insulin-likegrowth factor-binding protein 4 |
Gene ID : | 3487 |
mRNA Refseq : | NM_001552 |
Protein Refseq : | NP_001543 |
MIM : | 146733 |
UniProt ID : | P22692 |
Chromosome Location : | 17q12-q21.1 |
Function : | insulin-like growthfactor binding |
Products Types
◆ Recombinant Protein | ||
IGFBP4-2040R | Recombinant Rhesus Macaque IGFBP4 Protein, His (Fc)-Avi-tagged | +Inquiry |
IGFBP4-302H | Recombinant Human IGFBP4 Protein, His-tagged | +Inquiry |
IGFBP4-1385H | Recombinant Human IGFBP4 Protein | +Inquiry |
IGFBP4-8819C | Active Recombinant Cynomolgus IGFBP4 protein(Met1-Glu258), His-tagged | +Inquiry |
IGFBP4-4429H | Recombinant Human IGFBP4 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IGFBP4-1231CCL | Recombinant Cynomolgus IGFBP4 cell lysate | +Inquiry |
IGFBP4-2925MCL | Recombinant Mouse IGFBP4 cell lysate | +Inquiry |
IGFBP4-2926HCL | Recombinant Human IGFBP4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket