Recombinant Human Interferon Gamma Receptor 1
Cat.No. : | IFNGR1-57H |
- Specification
- Gene Information
- Related Products
Cat. No. : | IFNGR1-57H |
Description : | IFN-γ receptor ligand-binding chain (IFNγR1) or IFN-γ R α chain, also known CDw119, is member of the class II cytokine receptor family. The IFN-γ receptor is a complex of a high affinity IFN-γ-binding chain (aka, IFN-γ R α chain) and a second accessory protein required for signal transduction known as IFN-γ R β chain. Binding of IFN-γ induces receptor dimerization and internalization. Signal transduction involves Jak1 and Jak2 protein kinases and involves STAT1 activation. The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes. |
Source : | Mammalian cells |
Molecular Weight : | The predicted molecular weight of Recombinant Human IFN-γ R1 is Mr 25 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 40-50 kDa. |
State Of Matter : | Lyophilized. |
Purity : | > 95% by SDS Page and analyzed by silver stain. |
Endotoxin : | < 1.0 EU/µg as determined by the LAL method. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | IFNGR1 interferon gamma receptor 1 [ Homo sapiens ] |
Synonyms : | IFNGR1; interferon gamma receptor 1; CD119; IFNGR; FLJ45734; AVP, type 2; CD119 antigen; immune interferon receptor 1; interferon-gamma receptor alpha chain; IFN-gamma-R1; OTTHUMP00000017285; interferon gamma receptor 1 |
Gene ID : | 3459 |
mRNA Refseq : | NM_000416 |
Protein Refseq : | NP_000407 |
UniProt ID : | P15260 |
Chromosome Location : | 6q23-q24 |
MIM : | 107470 |
Pathway : | Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway; Natural killer cell mediated cytotoxicity |
Function : | cytokine binding; interferon-gamma receptor activity; receptor activity |
Products Types
◆ Recombinant Protein | ||
IFNGR1-298H | Recombinant Human IFNGR1 Protein, Fc-tagged | +Inquiry |
IFNGR1-1151H | Recombinant Human IFNGR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ifngr1-1652M | Recombinant Mouse Ifngr1 Protein, His-tagged | +Inquiry |
IFNGR1-062H | Recombinant Human IFNGR1 Protein, C-His-tagged | +Inquiry |
IFNGR1-297H | Recombinant Human IFNGR1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
IFNGR1-1003CCL | Recombinant Cynomolgus IFNGR1 cell lysate | +Inquiry |
IFNGR1-2646HCL | Recombinant Human IFNGR1 cell lysate | +Inquiry |
IFNGR1-1775MCL | Recombinant Mouse IFNGR1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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