| Description : |
INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1) and U2 (RNU2). |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
244.7 kDa |
| AA Sequence : |
MNRAKPTTVRRPSAAAKPSGHPPPG DFIALGSKGQANESKTASTLLKPAP SGLPSERKRDAAAALSSASALTGLT KRPKLSSTPPLSALGRLAEAAVAEK RAISPSIKEPSVVPIEVLPTVLLDE IEAAELEGNDDRIEGVLCGAVKQLK VTRAKPDSTLYLSLMYLAKIKPNIF ATEGVIEALCSLLRRDASINFKAKG NSLVSVLACNLLMAAYEEDENWPEI FVKVYIEDSLGERIWVDSPHCKTFV DNIQTAFNTRMPPRSVLLQGEAGRV AGDLGAGSSPHPSLTEEEDSQTELL IAEEKLSPEQEGQLMPRYEELAESV EEYVLDMLRDQLNRRQPIDNVSRNL LRLLTSTCGYKEVRLLAVQKLEMWL QNPKLTRPAQDLLMSVCMNCNTHGS EDMDVISHLIKIRLKPKVLLNHFML CIRELLSAHKDNLGTTIKLVIFNEL SSARNPNNMQVLYTALQHSSELAPK FLAMVFQDLLTNKDDYLRASRALLR EIIKQTKHEINFQAFCLGLMQERKE PQYLEMEFKERFVVHITDVLAVSMM LGITAQVKEAGIAWDKGEKRNLEVL RSFQNQIAAIQRDAVWWLHTVVPSI SKLAPKDYVHCLHKVLFTEQPETYY KWDNWPPESDRNFFLRLCSEVPILE DTLMRILVIGLSRELPLGPADAMEL ADHLVKRAAAVQADDVEVLKVGRTQ LIDAVLNLCTYHHPENIQLPPGYQP PNLAISTLYWKAWPLLLVVAAFNPE NIGLAAWEEYPTLKMLMEMVMTNNY SYPPCTLTDEETRTEMLNRELQTAQ REKQEILAFEGHLAAASTKQTITES SSLLLSQLTSLDPQGPPRRPPPHIL DQVKSLNQSLRLGHLLCRSRNPDFL LHIIQRQASSQSMPWLADLVQSSEG SLDVLPVQCLCEFLLHDAVDDAASG EEDDEGESKEQKAKKRQRQQKQRQL LGRLQDLLLGPKADEQTTCEVLDYF LRRLGSSQVASRVLAMKGLSLVLSE GSLRDGEEKEPPMEEDVGDTDVLQG YQWLLRDLPRLPLFDSVRSTTALAL QQAIHMETDPQTISAYLIYLSQHTP VEEQAQHSDLALDVARLVVERSTIM SHLFSKLSPSAASDAVLSALLSIFS RYVRRMRQSKEGEEVYSWSESQDQV FLRWSSGETATMHILVVHAMVILLT LGPPRADDSEFQALLDIWFPEEKPL PTAFLVDTSEEALLLPDWLKLRMIR SEVLRLVDAALQDLEPQQLLLFVQS FGIPVSSMSKLLQFLDQAVAHDPQT LEQNIMDKNYMAHLVEVQHERGASG GQTFHSLLTASLPPRRDSTEAPKPK SSPEQPIGQGRIRVGTQLRVLGPED DLAGMFLQIFPLSPDPRWQSSSPRP VALALQQALGQELARVVQGSPEVPG ITVRVLQALATLLSSPHGGALVMSM HRSHFLACPLLRQLCQYQRCVPQDT GFSSLFLKVLLQMLQWLDSPGVEGG PLRAQLRMLASQASAGRRLSDVRGG LLRLAEALAFRQDLEVVSSTVRAVI ATLRSGEQCSVEPDLISKVLQGLIE VRSPHLEELLTAFFSATADAASPFP ACKPVVVVSSLLLQEEEPLAGGKPG ADGGSLEAVRLGPSSGLLVDWLEML DPEVVSSCPDLQLRLLFSRRKGKGQ AQVPSFRPYLLTLFTHQSSWPTLHQ CIRVLLGKSREQRFDPSASLDFLWA CIHVPRIWQGRDQRTPQKRREELVL RVQGPELISLVELILAEAETRSQDG DTAACSLIQARLPLLLSCCCGDDES VRKVTEHLSGCIQQWGDSVLGRRCR DLLLQLYLQRPELRVPVPEVLLHSE GAASSSVCKLDGLIHRFITLLADTS DSRALENRGADASMACRKLAVAHPL LLLRHLPMIAALLHGRTHLNFQEFR QQNHLSCFLHVLGLLELLQPHVFRS EHQGALWDCLLSFIRLLLNYRKSSR HLAAFINKFVQFIHKYITYNAPAAI SFLQKHADPLHDLSFDNSDLVMLKS LLAGLSLPSRDDRTDRGLDEEGEEE SSAGSLPLVSVSLFTPLTAAEMAPY MKRLSRGQTVEDLLEVLSDIDEMSR RRPEILSFFSTNLQRLMSSAEECCR NLAFSLALRSMQNSPSIAAAFLPTF MYCLGSQDFEVVQTALRNLPEYALL CQEHAAVLLHRAFLVGMYGQMDPSA QISEALRILHMEAVMTRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
