Recombinant Human IRAK1
Cat.No. : | IRAK1-27502TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 530-693 of Human IRAK with an N terminal proprietary tag; Predicted MWt 43.45 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Protein length : | 164 amino acids |
Molecular Weight : | 43.450kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Isoform 1 and isoform 2 are ubiquitously expressed in all tissues examined, with isoform 1 being more strongly expressed than isoform 2. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | SSTGRAHSGAAPWQPLAAPSGASAQAAEQLQRGPNQPVES DESLGGLSAALRSWHLTPSCPLDPAPLREAGCPQGDTAGE SSWGSGPGSRPTAVEGLALGSSASSSSEPPQIIINPARQK MVQKLALYEDGALDSLQLLSSSSLPGLGLEQDRQGPEESD EFQS |
Sequence Similarities : | Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.Contains 1 protein kinase domain. |
Gene Name : | IRAK1 interleukin-1 receptor-associated kinase 1 [ Homo sapiens ] |
Official Symbol : | IRAK1 |
Synonyms : | IRAK1; interleukin-1 receptor-associated kinase 1; IRAK; pelle; |
Gene ID : | 3654 |
mRNA Refseq : | NM_001569 |
Protein Refseq : | NP_001560 |
MIM : | 300283 |
Uniprot ID : | P51617 |
Chromosome Location : | Xq28 |
Pathway : | Activated TLR4 signalling, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Chagas disease (American trypanosomiasis), organism-specific biosystem; Chagas disease (American trypanosomiasis), conserved biosystem; |
Function : | ATP binding; NF-kappaB-inducing kinase activity; interleukin-1 receptor binding; kinase activity; nucleotide binding; |
Products Types
◆ Recombinant Protein | ||
IRAK1-869H | Recombinant Human IRAK1 protein, His-tagged | +Inquiry |
IRAK1-1542H | Recombinant Human IRAK1 Protein, His tagged | +Inquiry |
IRAK1-799H | Recombinant Human IRAK1 Protein, GST/His-tagged | +Inquiry |
Irak1-1243M | Recombinant Mouse Irak1 Protein, MYC/DDK-tagged | +Inquiry |
IRAK1-5056H | Recombinant Human IRAK1 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
IRAK1-5173HCL | Recombinant Human IRAK1 293 Cell Lysate | +Inquiry |
IRAK1-5174HCL | Recombinant Human IRAK1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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