Recombinant Human IRF1 Protein, GST-tagged

• Cat.No.: IRF1-5046H
• Product Overview: Human IRF1 full-length ORF ( NP_002189.1, 1 a.a. - 325 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 61.38 kDa
• AA Sequence: MPITRMRMRPWLEMQINSNQIPGLI WINKEEMIFQIPWKHAAKHGWDINK DACLFRSWAIHTGRYKAGEKEPDPK TWKANFRCAMNSLPDIEEVKDQSRN KGSSAVRVYRMLPPLTKNQRKERKS KSSRDAKSKAKRKSCGDSSPDTFSD GLSSSTLPDDHSSYTVPGYMQDLEV EQALTPALSPCAVSSTLPDWHIPVE VVPDSTSDLYNFQVSPMPSTSEATT DEDEEGKLPEDIMKLLEQSEWQPTN VDGKGYLLNEPGVQPTSVYGDFSCK EEPEIDSPGGDIGLSLQRVFTDLKN MDATWLDSLLTPVRLPSIQAIPCAP
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: IRF1 interferon regulatory factor 1 [ Homo sapiens ]
• Official Symbol: IRF1
• Synonyms: IRF1; interferon regulatory factor 1; MAR; IRF-1
• Gene ID: 3659
• mRNA Refseq: NM_002198
• Protein Refseq: NP_002189
• MIM: 147575
• UniProt ID: P10914