Recombinant Human ISL1 Protein, GST-tagged

• Cat.No.: ISL1-5015H
• Product Overview: Human ISL1 full-length ORF ( NP_002193.1, 1 a.a. - 346 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 65.1 kDa
• AA Sequence: MGDPPKKKRLISLCVGCGNQIHDQY ILRVSPDLEWHAACLKCAECNQYLD ESCTCFVRDGKTYCKRDYIRLYGIK CAKCSIGFSKNDFVMRARSKVYHIE CFRCVACSRQLIPGDEFALREDGLF CRADHDVVERASLGAGDPLSPLHPA RPLQMAAEPISARQPALRPHVHKQP EKTTRVRTVLNEKQLHTLRTCYAAN PRPDALMKEQLVEMTGLSPRVIRVW FQNKRCKDKKRSIMMKQLQQQQPND KTNIQGMTGTPMVAASPERHDGGLQ ANPVEVQSYQPPWKVLSDFALQSDI DQPAFQQLVNFSEGGPGSNSTGSEV ASMSSQLPDTPNSMVASPIEA
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ISL1 ISL LIM homeobox 1 [ Homo sapiens ]
• Official Symbol: ISL1
• Synonyms: ISL1; ISL LIM homeobox 1; ISL1 transcription factor, LIM/homeodomain, (islet 1); insulin gene enhancer protein ISL-1; Isl 1; ISLET1; islet-1; ISL1 transcription factor, LIM/homeodomain; Isl-1
• Gene ID: 3670
• mRNA Refseq: NM_002202
• Protein Refseq: NP_002193
• MIM: 600366
• UniProt ID: P61371