Recombinant Human IVD Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: IVD-5996H
• Product Overview: IVD MS Standard C13 and N15-labeled recombinant protein (NP_002216) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia. Alternatively spliced transcript variants have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 46.2 kDa
• AA Sequence: MATATRLLGCRVASWRLRPPLAGFV SQRAHSLLPVDDAINGLSEEQRQLR QTMAKFLQEHLAPKAQEIDRSNEFK NLREFWKQLGNLGVLGITAPVQYGG SGLGYLEHVLVMEEISRASGAVGLS YGAHSNLCINQLVRNGNEAQKEKYL PKLISGEYIGALAMSEPNAGSDVVS MKLKAEKKGNHYILNGNKFWITNGP DADVLIVYAKTDLAAVPASRGITAF IVEKGMPGFSTSKKLDKLGMRGSNT CELIFEDCKIPAANILGHENKGVYV LMSGLDLERLVLAGGPLGLMQAVLD HTIPYLHVREAFGQKIGHFQLMQGK MADMYTRLMACRQYVYNVAKACDEG HCTAKDCAGVILYSAECATQVALDG IQCFGGNGYINDFPMGRFLRDAKLY EIGAGTSEVRRLVIGRAFNADFHTR TRPLEQKLISEEDLAANDILDYKDD DDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: IVD isovaleryl-CoA dehydrogenase [ Homo sapiens (human) ]
• Official Symbol: IVD
• Synonyms: IVD; isovaleryl-CoA dehydrogenase; isovaleryl CoA dehydrogenase, isovaleryl Coenzyme A dehydrogenase; isovaleryl-CoA dehydrogenase, mitochondrial; ACAD2; isovaleryl CoA dehydrogenase; isovaleryl Coenzyme A dehydrogenase; FLJ12715; FLJ34849
• Gene ID: 3712
• mRNA Refseq: NM_002225
• Protein Refseq: NP_002216
• MIM: 607036
• UniProt ID: P26440

Reviews

03/13/2019

After a prolonged quest, I have finally discovered such a steadfast and dependable protein reagent that plays an indispensable role in my research endeavors.

05/29/2017

This protein reagent is truly marvelous, providing stability and reliability, while becoming an invaluable assistant in my experiments.

07/19/2016

The unwavering high quality of this protein substance instills confidence in the accuracy of my experimental results.