| Description : |
Junctional complexes between the plasma membrane and endoplasmic/sarcoplasmic reticulum are a common feature of all excitable cell types and mediate cross talk between cell surface and intracellular ion channels. The protein encoded by this gene is a component of junctional complexes and is composed of a C-terminal hydrophobic segment spanning the endoplasmic/sarcoplasmic reticulum membrane and a remaining cytoplasmic domain that shows specific affinity for the plasma membrane. This gene is a member of the junctophilin gene family. Alternative splicing has been observed at this locus and two variants encoding distinct isoforms are described. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
74 kDa |
| AA Sequence : |
MSGGRFDFDDGGAYCGGWEGGKAHG HGLCTGPKGQGEYSGSWNFGFEVAG VYTWPSGNTFEGYWSQGKRHGLGIE TKGRWLYKGEWTHGFKGRYGIRQSS SSGAKYEGTWNNGLQDGYGTETYAD GGTYQGQFTNGMRHGYGVRQSVPYG MAVVVRSPLRTSLSSLRSEHSNGTV APDSPASPASDGPALPSPAIPRGGF ALSLLANAEAAARAPKGGGLFQRGA LLGKLRRAESRTSVGSQRSRVSFLK SDLSSGASDAASTASLGEAAEGADE AAPFEADIDATTTETYMGEWKNDKR SGFGVSERSSGLRYEGEWLDNLRHG YGCTTLPDGHREEGKYRHNVLVKDT KRRMLQLKSNKVRQKVEHSVEGAQR AAAIARQKAEIAASRTSHAKAKAEA AEQAALAANQESNIARTLARELAPD FYQPGPEYQKRRLLQEILENSESLL EPPDRGAGAAGLPQPPRESPQLHER ETPRPEGGSPSPAGTPPQPKRPRPG VSKDGLLSPGAWNGEPSGEGSRSVT PSEGAGRRSPARPATERMAIEALQA PPAPSREPEVALYQGYHSYAVRTTP PEPPPFEDQPEPEVSGSESAPSSPA TAPLQAPTLRGPEPARETPAKLEPK PIIPKAEPRAKARKTEARGLTKAGA KKKARKEAALAAEAEVEVEEVPNTI LICMVILLNIGLAILFVHLLTTRTR PLEQKLISEEDLAANDILDYKDDDD KV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
