Recombinant Human JPT1 Protein, His-tagged
Cat.No. : | JPT1-002H |
Product Overview : | Recombinant Human JPT1 Protein (1-181 aa (full-length)) with 6xHis tag was expressed in E. coli. |
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Description : | Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation (PubMed:22155408). |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 23.1 kDa |
Protein length : | 1-181 |
Purity : | >95% confirmed by 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-6xHis (WB). |
Applications : | ELISA, Western Blot, Antibody Production, Protein array |
Quality Control Test : | 10% SDS-PAGE stained with Coomassie Blue (CB), immunobloting with anti-GST monoclonal and peptide fingerprinting by MALDI-TOF mass spectrometry. |
Storage : | Store working aliquots at 4 centigrade for up to one week. For extended storage, conserve at −80 centigrade. |
Expiry : | 12 months from the date of purchase, if it is properly stored. |
Storage Buffer : | Phosphate-Buffered Saline (PBS), pH 7.4. No preservatives added. |
Shipping : | Dry Ice |
Gene Name : | JPT1 Jupiter microtubule associated homolog 1 [ Homo sapiens (human) ] |
Official Symbol : | JPT1 |
Synonyms : | JPT1; Jupiter microtubule associated homolog 1; HN1; ARM2; HN1A; jupiter microtubule associated homolog 1; androgen-regulated protein 2; hematological and neurological expressed 1 protein |
Gene ID : | 51155 |
mRNA Refseq : | NM_001002032 |
Protein Refseq : | NP_001002032 |
UniProt ID : | Q9UK76 |
Products Types
◆ Recombinant Protein | ||
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JPT1-4890H | Recombinant Human JPT1 Protein, GST-tagged | +Inquiry |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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