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Recombinant Human KARS Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : KARS-6605H
Product Overview : KARS MS Standard C13 and N15-labeled recombinant protein (NP_005539) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
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Description : Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 68 kDa
AA Sequence : MAAVQAAEVKVDGSEPKLSKNELKR RLKAEKKVAEKEAKQKELSEKQLSQ ATAAATNHTTDNGVGPEEESVDPNQ YYKIRSQAIHQLKVNGEDPYPHKFH VDISLTDFIQKYSHLQPGDHLTDIT LKVAGRIHAKRASGGKLIFYDLRGE GVKLQVMANSRNYKSEEEFIHINNK LRRGDIIGVQGNPGKTKKGELSIIP YEITLLSPCLHMLPHLHFGLKDKET RYRQRYLDLILNDFVRQKFIIRSKI ITYIRSFLDELGFLEIETPMMNIIP GGAVAKPFITYHNELDMNLYMRIAP ELYHKMLVVGGIDRVYEIGRQFRNE GIDLTHNPEFTTCEFYMAYADYHDL MEITEKMVSGMVKHITGSYKVTYHP DGPEGQAYDVDFTPPFRRINMVEEL EKALGMKLPETNLFETEETRKILDD ICVAKAVECPPPRTTARLLDKLVGE FLEVTCINPTFICDHPQIMSPLAKW HRSKEGLTERFELFVMKKEICNAYT ELNDPMRQRQLFEEQAKAKAAGDDE AMFIDENFCTALEYGLPPTAGWGMG IDRVAMFLTDSNNIKEVLLFPAMKP EDKKENVATTDTLESTTVGTSVTRT RPLEQKLISEEDLAANDILDYKDDD DKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : KARS lysyl-tRNA synthetase [ Homo sapiens (human) ]
Official Symbol : KARS
Synonyms : KARS; lysyl-tRNA synthetase; lysine--tRNA ligase; KARS2; lysine tRNA ligase; lysRS; KRS; CMTRIB; KIAA0070;
Gene ID : 3735
mRNA Refseq : NM_005548
Protein Refseq : NP_005539
MIM : 601421
UniProt ID : Q15046

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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