Recombinant Human KCTD17 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: KCTD17-3142H
• Product Overview: KCTD17 MS Standard C13 and N15-labeled recombinant protein (NP_078957) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein that belongs to a conserved family of potassium channel tetramerization domain (KCTD)-containing proteins. The encoded protein functions in ciliogenesis by acting as a substrate adaptor for the cullin3-based ubiquitin-conjugating enzyme E3 ligase, and targets trichoplein, a keratin-binding protein, for degradation via polyubiquitinylation. A mutation in this gene is associated with autosomal dominant myoclonic dystonia 26.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 32.5 kDa
• AA Sequence: MRMEAGEAAPPAGAGGRAAGGWGKW VRLNVGGTVFLTTRQTLCREQKSFL SRLCQGEELQSDRDETGAYLIDRDP TYFGPILNFLRHGKLVLDKDMAEEG VLEEAEFYNIGPLIRIIKDRMEEKD YTVTQVPPKHVYRVLQCQEEELTQM VSTMSDGWRFEQLVNIGSSYNYGSE DQAEFLCVVSKELHSTPNGLSSESS RKTKSTEEQLEEQQQQEEEVEEVEV EQVQVEADAQEKGSRPHPLRPEAEL AVRASPRPLARPQSCHPCCYKPEAP GCEAPDHLQGLGVPITRTRPLEQKL ISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: KCTD17 potassium channel tetramerisation domain containing 17 [ Homo sapiens (human) ]
• Official Symbol: KCTD17
• Synonyms: KCTD17; potassium channel tetramerisation domain containing 17; BTB/POZ domain-containing protein KCTD17; FLJ12242; FLJ98761
• Gene ID: 79734
• mRNA Refseq: NM_024681
• Protein Refseq: NP_078957
• MIM: 616386
• UniProt ID: Q8N5Z5