Recombinant Human KDM3B Protein, His-tagged

• Cat.No.: KDM3B-2358H
• Product Overview: Recombinant Human KDM3B Protein (Met1498-Arg1721) with a N-His tag was expressed in E. coli.

Specification

• Description: Predicted to enable chromatin DNA binding activity; histone H3-methyl-lysine-9 demethylase activity; and transcription coregulator activity. Predicted to be involved in histone H3-K9 demethylation and regulation of transcription by RNA polymerase II. Located in nucleoplasm. Biomarker of acute lymphoblastic leukemia; breast cancer; colorectal cancer; and lung non-small cell carcinoma.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 29.2 kDa
  Accurate Molecular Mass: 29 kDa
• Protein length: Met1498-Arg1721
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: KDM3B lysine (K)-specific demethylase 3B [ Homo sapiens (human) ]
• Official Symbol: KDM3B
• Synonyms: KDM3B; lysine (K)-specific demethylase 3B; C5orf7, chromosome 5 open reading frame 7, JMJD1B, jumonji domain containing 1B; lysine-specific demethylase 3B; KIAA1082; NET22; nuclear protein 5qNCA; jumonji domain containing 1B; jumonji domain-containing protein 1B; jmjC domain-containing histone demethylation protein 2B; 5qNCA; C5orf7; JMJD1B
• Gene ID: 51780
• mRNA Refseq: NM_016604
• Protein Refseq: NP_057688
• MIM: 609373
• UniProt ID: Q7LBC6