Recombinant Human KDM4A, GST-tagged
Cat.No. : | KDM4A-7031H |
Product Overview : | Recombinant human KDM4A (1-886) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | KDM4A or lysine (K)-specific demethylase 4A is a member of the Jumonji domain 2 (JMJD2) family that encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. KDM4A functions in euchromatin to remove histone methylation marks that are associated with active transcription. KDM4A also act as a trimethylation-specific demethylase those converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. |
Source : | Sf9 Cells |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~150 kDa |
Protein length : | 1-886 aa |
Purity : | >90% |
Applications : | Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1 μg/μl |
Gene Name : | KDM4A lysine (K)-specific demethylase 4A [ Homo sapiens ] |
Official Symbol : | KDM4A |
Synonyms : | KDM4A; lysine (K)-specific demethylase 4A; JMJD2, JMJD2A, jumonji domain containing 2 , jumonji domain containing 2A; lysine-specific demethylase 4A; JHDM3A; jumonji C domain containing histone demethylase 3A; KIAA0677; jumonji domain containing 2; jumonji domain containing 2A; jumonji domain-containing protein 2A; jumonji C domain-containing histone demethylase 3A; jmjC domain-containing histone demethylation protein 3A; JMJD2; JMJD2A; |
Gene ID : | 9682 |
mRNA Refseq : | NM_014663 |
Protein Refseq : | NP_055478 |
MIM : | 609764 |
UniProt ID : | O75164 |
Chromosome Location : | 1p34.1 |
Function : | histone demethylase activity (H3-K36 specific); metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; protein binding; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
KDM4A-018H | Recombinant Human KDM4A Protein, His-tagged | +Inquiry |
KDM4A-010H | Recombinant Human KDM4A Protein, Strep II-tagged | +Inquiry |
KDM4A-4779M | Recombinant Mouse KDM4A Protein, His (Fc)-Avi-tagged | +Inquiry |
Kdm4a-3681M | Recombinant Mouse Kdm4a Protein, Myc/DDK-tagged | +Inquiry |
KDM4A-0531H | Recombinant Human KDM4A Protein (M1-L359), Tag Free | +Inquiry |
◆ Lysates | ||
KDM4A-4996HCL | Recombinant Human KDM4A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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