| Description : |
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
80.1 kDa |
| AA Sequence : |
MAAAAVAAAAAAAAAASLQVLEMES METAAAGSAGLAAEVRGSGTVDFGP GPGISAMEASGGDPGPEAEDFECSS HCSELSWRQNEQRRQGLFCDITLCF GGAGGREFRAHRSVLAAATEYFTPL LSGQFSESRSGRVEMRKWSSEPGPE PDTVEAVIEYMYTGRIRVSTGSVHE VLELADRFLLIRLKEFCGEFLKKKL HLSNCVAIHSLAHMYTLSQLALKAA DMIRRNFHKVIQDEEFYTLPFHLIR DWLSDLEITVDSEEVLFETVLKWVQ RNAEERERYFEELFKLLRLSQMKPT YLTRHVKPERLVANNEVCVKLVADA VERHALRAENIQSGTCQHPTSHVSL LPRYGQNMDVIMVIGGVSEGGDYLS ECVGYFVDEDRWVNLPHIHNHLDGH AVAVTESYVYVAGSMEPGFAKTVER YNPNLNTWEHVCSLMTRKHSFGLTE VKGKLYSIGGHGNFSPGFKDVTVYN PELDKWHNLESAPKILRDVKALAIE DRFVYIAARTPVDRDTEDGLKAVIT CYDTETRQWQDVESLPLIDNYCFFQ MSVVNSNFYQTASCCPKSYCLENEE AVRKIASQVSDEILESLPPEVLSIE GAAICYYKDDVFIIGGWKNSDDIDK QYRKEAYRYCAERKRWMLLPPMPQP RCRATACHVRIPYRYLHGTQRYPMP QNLMWQKDRIRQMQEIHRHALNMRR VPSSQIECTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
