| Description : |
The protein encoded by this gene is expressed in neurons of most regions of the brain. It contains an N-terminal BTB domain, which mediates dimerization of the protein, and a C-terminal Kelch domain, which mediates binding to F-actin. This protein may play a key role in the regulation of actin-based neuronal function. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
69.7 kDa |
| AA Sequence : |
MQPRSERPAGRTQSPEHGSPGPGPE APPPPPPQPPAPEAERTRPRQARPA APMEGAVQLLSREGHSVAHNSKRHY HDAFVAMSRMRQRGLLCDIVLHVAA KEIRAHKVVLASCSPYFHAMFTNEM SESRQTHVTLHDIDPQALDQLVQFA YTAEIVVGEGNVQTLLPAASLLQLN GVRDACCKFLLSQLDPSNCLGIRGF ADAHSCSDLLKAAHRYVLQHFVDVA KTEEFMLLPLKQVLELVSSDSLNVP SEEEVYRAVLSWVKHDVDARRQHVP RLMKCVRLPLLSRDFLLGHVDAESL VRHHPDCKDLLIEALKFHLLPEQRG VLGTSRTRPRRCEGAGPVLFAVGGG SLFAIHGDCEAYDTRTDRWHVVASM STRRARVGVAAVGNRLYAVGGYDGT SDLATVESYDPVTNTWQPEVSMGTR RSCLGVAALHGLLYSAGGYDGASCL NSAERYDPLTGTWTSVAAMSTRRRY VRVATLDGNLYAVGGYDSSSHLATV EKYEPQVNVWSPVASMLSRRSSAGV AVLEGALYVAGGNDGTSCLNSVERY SPKAGAWESVAPMNIRRSTHDLVAM DGWLYAVGGNDGSSSLNSIEKYNPR TNKWVAASCMFTRRSSVGVAVLELL NFPPPSSPTLSVSSTSLTRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
