Recombinant Human KPTN Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: KPTN-4089H
• Product Overview: KPTN MS Standard C13 and N15-labeled recombinant protein (NP_008990) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a filamentous-actin-associated protein, which is involved in actin dynamics and plays an important role in neuromorphogenesis. This protein is part of the KICSTOR protein complex that localizes to lysosomes. Mutations in this gene result in an autosomal recessive form of intellectual disability. Alternatively spliced transcript variants have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 48.1 kDa
• AA Sequence: MMGEAAVAAGPCPLREDSFTRFSSQ SNVYGLAGGAGGRGELLAATLKGKV LGFRYQDLRQKIRPVAKELQFNYIP VDAEIVSIDTFNKSPPKRGLVVGIT FIKDSGDKGSPFLNIYCDYEPGSEY NLDSIAQSCLNLELQFTPFQLCHAE VQVGDQLETVFLLSGNDPAIHLYKE NEGLHQFEEQPVENLFPELTNLTSS VLWLDVHNFPGTSRRLSALGCQSGY VRVAHVDQRSREVLQMWSVLQDGPI SRVIVFSLSAAKETKDRPLQDEYSV LVASMLEPAVVYRDLLNRGLEDQLL LPGSDQFDSVLCSLVTDVDLDGRPE VLVATYGQELLCYKYRGPESGLPEA QHGFHLLWQRSFSSPLLAMAHVDLT GDGLQELAVVSLKGVHILQHSLIQA SELVLTRLRHQVEQRRRRLQGLEDG AGAGPAENAASTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: KPTN kaptin, actin binding protein [ Homo sapiens (human) ]
• Official Symbol: KPTN
• Synonyms: KPTN; kaptin (actin binding protein); kaptin; 2E4; actin-associated protein 2E4; kaptin (actin-binding protein)
• Gene ID: 11133
• mRNA Refseq: NM_007059
• Protein Refseq: NP_008990
• MIM: 615620
• UniProt ID: Q9Y664