Recombinant Human LAG3 Protein, His\Avi-tagged
Cat.No. : | LAG3-196H |
Product Overview : | Biotinylated Recombinant Human Lymphocyte Activation Gene 3 Protein is produced by our Mammalian expression system and the target gene encoding Leu23-Leu450 is expressed with a 6His, Avi tag at the C-terminus. |
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- Gene Information
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Description : | Human Lymphocyte activation gene 3 protein( LAG3) is a member of immunoglobulin (Ig) superfamily. LAG3 contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. LAG3 is involved in lymphocyte activation and can bind to HLA class-II antigens. It is selectively expressed in activated T and NK cells. LAG3 has a negative regulatory function in T cells and acts as as a new marker of T cell induced B cell activation. As a soluble molecule, LAG3 activates antigen-presenting cells through MHC class II signaling. It can lead to increased antigen-specific T-cell responses in vivo. LAG-3 has higher affinity to MHC class II than CD4. |
Source : | Human Cells |
Species : | Human |
Tag : | His\Avi |
Form : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
AA Sequence : | Leu23-Leu450 |
Endotoxin : | Less than 0.1 ng/ug (1 EU/ug). |
Shipping : | Ambient |
Gene Name : | LAG3 lymphocyte activating 3 [ Homo sapiens (human) ] |
Official Symbol : | LAG3 |
Synonyms : | Lymphocyte activation gene 3 protein; LAG-3; Protein FDC; CD223 |
Gene ID : | 3902 |
mRNA Refseq : | NM_002286.6 |
Protein Refseq : | NP_002277.4 |
MIM : | 153337 |
UniProt ID : | P18627 |
Products Types
◆ Lysates | ||
LAG3-941RCL | Recombinant Rat LAG3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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