Recombinant Human LAMP1 Protein, His-tagged

• Cat.No.: LAMP1-247H
• Product Overview: Recombinant Human LAMP1(29-382aa) fused with His tag at C-terminal was expressed in Insect cells.

Specification

• Description: LAMP1, also known as lysosome-associated membrane glycoprotein 1, is a membrane protein that belongs to the LAMP family. It is expressed in the endosome-lysosome membranes of cells, but is also found on the plasma membrane during the activation of NK cells, CD8+ T cells, mast cells, basophils, monocytes, and platelets. A glycoform of LAMP1 is expressed on the surface of activated macrophages where it promotes T cell co-stimulation and a Th1 biased immune response.
• Source: Insect cells
• Species: Human
• Tag: His
• Predicted N Terminal: Ala
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
• Molecular Mass: 39.4kDa (363aa) 57-70KDa (SDS-PAGE under reducing conditions.)
• Protein length: 29-382aa
• AA Sequence: ADPAMFMVKN GNGTACIMAN FSAAFSVNYD TKSGPKNMTF DLPSDATVVL NRSSCGKENT SDPSLVIAFG RGHTLTLNFT RNATRYSVQL
  MSFVYNLSDT HLFPNASSKE IKTVESITDI RADIDKKYRC VSGTQVHMNN VTVTLHDATI QAYLSNSSFS RGETRCEQDR PSPTTAPPAP
  PSPSPSPVPK SPSVDKYNVS GTNGTCLLAS MGLQLNLTYE RKDNTTVTRL LNINPNKTSA SGSCGAHLVT LELHSEGTTV LLFQFGMNAS
  SSRFFLQGIQ LNTILPDARD PAFKAANGSL RALQATVGNS YKCNAEEHVR VTKAFSVNIF KVWVQAFKVE GGQFGSVEEC LLDENSMHHH
  HHH
• Purity: > 90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: LAMP1 lysosomal-associated membrane protein 1 [ Homo sapiens ]
• Official Symbol: LAMP1
• Synonyms: LAMP1; lysosomal-associated membrane protein 1; lysosome-associated membrane glycoprotein 1; CD107a; LAMP-1; CD107 antigen-like family member A; lysosome-associated membrane protein 1; LAMPA; LGP120
• Gene ID: 3916
• mRNA Refseq: NM_005561
• Protein Refseq: NP_005552
• MIM: 153330
• UniProt ID: P11279