Recombinant Human LGMN Protein, MYC/DDK-tagged
Cat.No. : | LGMN-526H |
Product Overview : | Recombinant human LGMN protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008] |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
Molecular Mass : | 47.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | legumain[ Homo sapiens ] |
Official Symbol : | LGMN |
Synonyms : | AEP; LGMN1; PRSC1 |
Gene ID : | 5641 |
mRNA Refseq : | NM_005606.6 |
Protein Refseq : | NP_005597.3 |
MIM : | 602620 |
UniProt ID : | Q99538 |
Products Types
◆ Recombinant Protein | ||
LGMN-2161H | Recombinant Human LGMN Protein (18-323 aa), His-tagged | +Inquiry |
Lgmn-5062M | Recombinant Mouse Lgmn Protein, His (Fc)-Avi-tagged | +Inquiry |
Lgmn-3778M | Recombinant Mouse Lgmn Protein, Myc/DDK-tagged | +Inquiry |
LGMN-3050R | Recombinant Rat LGMN Protein, His (Fc)-Avi-tagged | +Inquiry |
LGMN-2549C | Recombinant Cynomolgus Monkey LGMN Protein (18-323 aa), His-Myc-tagged | +Inquiry |
◆ Lysates | ||
LGMN-2893MCL | Recombinant Mouse LGMN cell lysate | +Inquiry |
LGMN-001SCL | Recombinant Sus scrofa (Pig) LGMN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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