Recombinant Human LHPP, His-tagged

• Cat.No.: LHPP-28094TH
• Product Overview: Recombinant full length Human LHPP fused to an N terminal His and DDDDK tag, 307 amino acids predicted Mwt: 33.5 kDa inclusive of tags

Specification

• Description: LHPP is a member of the HAD-like hydrolase superfamily. It is a unique enzyme that hydrolyzes not only oxygen-phosphorus bonds in inorganic pyrophosphate but also nitrogen-phosphorus bonds in phospholysine, phosphohistidine and imidodiphosphate in vitro.
• Protein length: 270 amino acids
• Conjugation: HIS
• Molecular Weight: 33.500kDa inclusive of tags
• Source: E. coli
• Tissue specificity: Expressed in liver, kidney and moderately in brain.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:10% Glycerol, 0.32% Tris HCl, 0.02% DTT, 0.58% Sodium chloride
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MRGSHHHHHP WYASMTGGQQ MGRDLYDDDD KDRWGSHMAP WGKRLAGVRG VLLDISGVLY DSGAGGGTAI AGSVEAVARL KRSRLKVRFC TNESQKSRAE LVGQLQRLGF DISEQEVTAP APAACQILKE QGLRPYLLIH DGVRSEFDQI DTSNPNCVVI ADAGESFSYQ NMNNAFQVLM ELEKPVLISL GKGRYYKETS GLMLDVGPYM KALEYACGIK AEVVGKPSPE FFKSALQAIG VEAHQAVMIG DDIVGDVGGA QRCGMRALQV RTGKFRPSDE HHPEVKADGY VDNLAEAVDL LLQHADK
• Sequence Similarities: Belongs to the HAD-like hydrolase superfamily.

Gene Information

• Gene Name: LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase [ Homo sapiens ]
• Official Symbol: LHPP
• Synonyms: LHPP; phospholysine phosphohistidine inorganic pyrophosphate phosphatase; HDHD2B
• Gene ID: 64077
• mRNA Refseq: NM_022126
• Protein Refseq: NP_071409
• Uniprot ID: Q9H008
• Chromosome Location: 10q26.2
• Pathway: Oxidative phosphorylation, organism-specific biosystem; Oxidative phosphorylation, conserved biosystem
• Function: hydrolase activity; inorganic diphosphatase activity; magnesium ion binding; phosphohistidine phosphatase activity; protein homodimerization activity