Recombinant Human LILRA4 protein, His-Avi-tagged
Cat.No. : | LILRA4-901H |
Product Overview : | Human LILRA4 Protein is expressed from mammalian with His and Avi Tag at the C-terminal. It contains Glu24-Asn446. |
- Specification
- Gene Information
- Related Products
Description : | LILRA4, also known as ILT7 and CD85g, is an approximately 60-70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. Mature human LILRA4 consists of a 423 amino acid (aa) extracellular domain (ECD) with four immunoglobulin-like domains, a 21 aa transmembrane segment, and a 32 aa cytoplasmic domain.LILRA4 function coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G (PubMed:16735691, PubMed:19564354). Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades. |
Source : | HEK293 |
Species : | Human |
Tag : | His-Avi |
Form : | Supplied as 0.22um filtered solution in PBS (pH 7.4). |
Molecular Mass : | The protein has a predicted MW of 49.5 kDa .Due to glycosylation, the protein migrates to 60-75 KDa based on Bis-Tris PAGE result. |
Protein length : | Glu24-Asn446 |
Endotoxin : | Less than 0.2 EU per ug by the LAL method. |
Purity : | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Storage : | The product should be stored at -70°C. Please do not repeated freeze-thaw cycles. |
Gene Name : | LILRA4 leukocyte immunoglobulin like receptor A4 [ Homo sapiens (human) ] |
Official Symbol : | LILRA4 |
Synonyms : | CD85 antigen-like family member G; CD85g antigen; CD85g; ILT7; ILT-7; ILT7MGC129598; Immunoglobulin-like transcript 7; leukocyte immunoglobulin-like receptor subfamily A member 4; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4; leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member4; LILRA4; MGC129597 |
Gene ID : | 23547 |
mRNA Refseq : | NM_012276.5 |
Protein Refseq : | NP_036408.4 |
MIM : | 607517 |
UniProt ID : | P59901 |
Products Types
◆ Recombinant Protein | ||
LILRA4-633H | Recombinant Human LILRA4 Protein (Met1-Asn446), His-tagged | +Inquiry |
LILRA4-4152H | Recombinant Human LILRA4 Protein (Met1-Asn446), C-His tagged | +Inquiry |
LILRA4-579H | Recombinant Human LILRA4, His-tagged | +Inquiry |
LILRA4-166H | Recombinant Human LILRA4 Protein, Glu24-Asn446, C-His-Avi tagged, Biotinylated | +Inquiry |
LILRA4-634C | Recombinant Cynomolgus LILRA4 protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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