Recombinant Human LILRB5 protein, Fc & Avi-tagged, Biotinylated

• Cat.No.: LILRB5-0624H
• Product Overview: Biotinylated Human LILRB5 / CD85c / LIR-8, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Gly 458 (Accession # O75023-1). Biotinylation of this product is performed using Avitag technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin. The biotin to protein ratio is 0.5-1 as determined by the HABA assay.

Specification

• Description: Leukocyte immunoglobulin-like receptor subfamily B member 5 (LILRB5), also known as CD85c and LIR-8, belongs to the leukocyte immunoglobulin-like receptor (LIR) family of transmembrane glycoproteins that negatively regulate immune cell activation. Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response.
• Source: HEK293
• Species: Human
• Tag: Fc & Avi
• Predicted N Terminal: Gly 24
• Form: Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5, 10% trehalose.
• Molecular Mass: The protein has a calculated MW of 75.8 kDa. The protein migrates as 90-105 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Protein length: Gly 24 - Gly 458
• Endotoxin: Less than 1.0 EU per μg by the LAL method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles. No activity loss is observed after storage at: 4-8°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.
• Shipping: Powder,RT

Gene Information

• Gene Name: LILRB5 leukocyte immunoglobulin like receptor B5 [ Homo sapiens (human) ]
• Official Symbol: LILRB5
• Synonyms: LIR8; CD85C; LIR-8; CD85 antigen-like family member C; leucocyte Ig-like receptor B5; leukocyte immunoglobulin-like receptor 8; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5; leukocyte immunoglobulin-like receptor subfamily B member 5
• Gene ID: 10990
• mRNA Refseq: NM_001081442.2
• Protein Refseq: NP_001074911.1
• UniProt ID: O75023