Recombinant Human LMX1B, His-tagged
Cat.No. : | LMX1B-237H |
Product Overview : | LMX1B, 1-395aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | LMX1B is a member of LIM-homeodomain family of proteins containing two N-terminal zinc-binding LIM domains, 1 homeodomain, and a C-terminal glutamine-rich domain. It functions as a transcription factor, and is essential for the normal development of dorsal limb structures, the glomerular basement membrane, the anterior segment of the eye, and dopaminergic and serotonergic neurons. Mutations in this gene are associated with nail-patella syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Recombinant human LMX1B protein, fused to His-tag at N-terminus, was expressed in E.coli . |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | iquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea |
Molecular Mass : | 46.5 kDa (418 aa) |
Protein length : | 1-395aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMDIATGP ESLERCFPRG QTDCAKMLDG IKMEEHALRP GPATLGVLLG SDCPHPAVCE GCQRPISDRF LMRVNESSWH EECLQCAACQ QALTTSCYFR DRKLYCKQDY QQLFAAKCSG CMEKIAPTEF VMRALECVYH LGCFCCCVCE RQLRKGDEFV LKEGQLLCKG DYEKEKDLLS SVSPDESDSV KSEDEDGDMK PAKGQGSQSK GSGDDGKDPR RPKRPRTILT TQQRRAFKAS FEVSSKPCRK VRETLAAETG LSVRVVQVWF QNQRAKMKKL ARRHQQQQEQ QNSQRLGQEV LSSRMEGMMA SYTPLAPPQQ QIVAMEQSPY GSSDPFQQGL TPPQMPGNDS IFHDIDSDTS LTSLSDCFLG SSDVGSLQAR VGNPIDRLYS MQSSYFAS |
Purity : | >80 % by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1.0 mg/ml (determined by Bradford assay) |
Gene Name : | LMX1B LIM homeobox transcription factor 1, beta [ Homo sapiens ] |
Official Symbol : | LMX1B |
Synonyms : | LMX1B; LIM homeobox transcription factor 1, beta; NPS1; LIM homeobox transcription factor 1-beta; LMX-1.2; LIM/homeobox protein 1.2; LIM/homeobox protein LMX1B; LMX1.2; MGC138325; MGC142051; |
Gene ID : | 4010 |
mRNA Refseq : | NM_001174146 |
Protein Refseq : | NP_001167617 |
MIM : | 602575 |
UniProt ID : | O60663 |
Chromosome Location : | 9q33.3 |
Pathway : | SIDS Susceptibility Pathways, organism-specific biosystem; |
Function : | metal ion binding; protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
LMX1B-5122M | Recombinant Mouse LMX1B Protein, His (Fc)-Avi-tagged | +Inquiry |
LMX1B-9165M | Recombinant Mouse LMX1B Protein | +Inquiry |
LMX1B-6910C | Recombinant Chicken LMX1B | +Inquiry |
LMX1B-600H | Recombinant Human LMX1B, His-tagged | +Inquiry |
◆ Lysates | ||
LMX1B-383HCL | Recombinant Human LMX1B lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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