Recombinant Human LOX Protein, GST-tagged

• Cat.No.: LOX-4734H
• Product Overview: Human LOX full-length ORF (BAG35200.1, 1 a.a. - 417 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 73.3 kDa
• AA Sequence: MRFAWTVLLLGPLQLCALVHCAPPA AGQQQPPREPPAAPGAWRQQIQWEN NGQVFSLLSLGSQYQPQRRRDPGAA VPGAANASAQQPRTPILLIRDNRTA AARTRTAGSSGVTAGRPRPTARHWF QAGYSTSRAREAGASRAENQTAPGE VPALSNLQPPSRVDGMVGDDPYNPY KYSDDNPYYNYYDTYERPRPGGRYR PGYGTGYFQYGLPDLVADPYYIQAS TYVQKMSMYNLRCAAEENCLASTAY RADVRDYDHRVLLRFPQRVKNQGTS DFLPSRPRYSWEWHSCHQHYHSMDE FSHYDLLDANTQRRVAEGHKASFCL EDTSCDYGYHRRFACTAHTQGLSPG CYDTYGADIDCQWIDITDVKPGNYI LKVSVNPSYLVPESDYTNNVVRCDI RYTGHHAYASGCTISPY
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: LOX lysyl oxidase [ Homo sapiens ]
• Official Symbol: LOX
• Synonyms: LOX; lysyl oxidase; protein-lysine 6-oxidase; MGC105112
• Gene ID: 4015
• mRNA Refseq: NM_001178102
• Protein Refseq: NP_001171573
• MIM: 153455
• UniProt ID: P28300