Recombinant Human LRP5 Protein, GST-tagged
Cat.No. : | LRP5-4689H |
Product Overview : | Human LRP5 partial ORF ( NP_002326.1, 41 a.a. - 130 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 35.64 kDa |
AA Sequence : | RDVRLVDAGGVKLESTIVVSGLEDA AAVDFQFSKGAVYWTDVSEEAIKQT YLNQTGAAVQNVVISGLVSPDGLAC DWVGKKLYWTDSETN |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | LRP5 low density lipoprotein receptor-related protein 5 [ Homo sapiens ] |
Official Symbol : | LRP5 |
Synonyms : | LRP5; low density lipoprotein receptor-related protein 5; EVR1, exudative vitreoretinopathy 1 , LRP7, OPPG, osteoporosis pseudoglioma syndrome; low-density lipoprotein receptor-related protein 5; BMND1; HBM; LR3; OPS; LRP-5; low density lipoprotein receptor-related protein 7; EVR1; EVR4; LRP7; OPPG; OPTA1; VBCH2; |
Gene ID : | 4041 |
mRNA Refseq : | NM_002335 |
Protein Refseq : | NP_002326 |
MIM : | 603506 |
UniProt ID : | O75197 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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