Recombinant Human LYNA, GST-tagged
Cat.No. : | LYNA-759H |
Product Overview : | Recombinant Human LYNA protein (Met 1 - Pro 512), fused with the GST tag at the N-terminus, was expressed inBaculovirus. |
- Specification
- Gene Information
- Related Products
Cat. No. : | LYNA-759H |
Description : | V-yes-1 Yamaguchi sarcoma viral related oncogene homolog, also known as LYN, is a member of the Src family of protein tyrosine kinases, which is mainly expressed in hematopoietic cells and in neural tissues. In various hematopoietic cells, LYN has emerged as a key enzyme involved in the regulation of cell activation. In these cells, a small amount of LYN is associated with cell surface receptor proteins, including the B cell antigen receptor (BCR), CD40, or CD19. Following engagement of the B cell receptors, LYN undergoes rapid phosphorylation and activation. |
Source : | Baculovirus. |
Molecular Mass : | The recombinant human LYN / GST chimera consists of 736 amino acids and predicts a molecular mass of 84.8 kDa. It migrates as an approximately 75 kDa band in SDS-PAGE under reducing conditions. |
Predicted N Terminal : | Met. |
Purity : | > 94% as determined by SDS-PAGE. |
Formulation : | Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0 , 0.5mM Reduced Glutathione, 10%gly, 0.5mM PMSF. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Reconstitution : | A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. |
Storage And Stability : | Store it under sterile conditions at -700C. It is recommended that the protein be aliquoted for optimal storage and usage. Avoid repeated freeze-thaw cycles. |
Gene Name : | LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog [ Homo sapiens ] |
Synonyms : | LYN; v-yes-1 Yamaguchi sarcoma viral related oncogene homolog; JTK8; FLJ26625; Yamaguchi sarcoma viral (v-yes-1) related oncogene homolog; EC 2.7.10.2 |
Gene ID : | 4067 |
mRNA Refseq : | NM_001111097 |
Protein Refseq : | NP_001104567 |
MIM : | 165120 |
UniProt ID : | P07948 |
Chromosome Location : | 8q13 |
Pathway : | B cell receptor signaling pathway; Chemokine signaling pathway; Epithelial cell signaling in Helicobacter pylori infection; Fc epsilon RI signaling pathway; Fc gamma R-mediated phagocytosis; Hemostasis; Signaling in Immune system; Fc epsilon RI signaling pathway |
Function : | ATP binding; glycosphingolipid binding; integrin binding; non-membrane spanning protein tyrosine kinase activity; phosphoprotein binding; platelet-derived growth factor receptor binding; receptor signaling protein tyrosine kinase activity; transferase activity; ubiquitin protein ligase binding |
Products Types
◆ Recombinant Protein | ||
LYNA-344H | Recombinant Human LYNA, GST-tagged, Active | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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