| Description : |
MACC1 is a key regulator of the hepatocyte growth factor (HGF)-HGF receptor (HGFR, or MET) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
96.5 kDa |
| AA Sequence : |
MLITERKHFRSGRIAQSMSEANLID MEAGKLSKSCNITECQDPDLLHNWP DAFTLRGNNASKVANPFWNQLSASN PFLDDITQLRNNRKRNNISILKEDP FLFCREIENGNSFDSSGDELDVHQL LRQTSSRNSGRSKSVSELLDILDDT AHAHQSIHNSDQILLHDLEWLKNDR EAYKMAWLSQRQLARSCLDLNTISQ SPGWAQTQLAEVTIACKVNHQGGSV QLPESDITVHVPQGHVAVGEFQEVS LRAFLDPPHMLNHDLSCTVSPLLEI MLGNLNTMEALLLEMKIGAEVRKDP FSQVMTEMVCLHSLGKEGPFKVLSN CYIYKDTIQVKLIDLSQVMYLVVAA QAKALPSPAATIWDYIHKTTSIGIY GPKYIHPSFTVVLTVCGHNYMPGQL TISDIKKGGKNISPVVFQLWGKQSF LLDKPQDLSISIFSCDPDFEVKTEG ERKEIKQKQLEAGEVVHQQFLFSLV EHREMHLFDFCVQVEPPNGEPVAQF SITTPDPTPNLKRLSNLPGYLQKKE EIKSAPLSPKILVKYPTFQDKTLNF SNYGVTLKAVLRQSKIDYFLEYFKG DTIALLGEGKVKAIGQSKVKEWYVG VLRGKIGLVHCKNVKVISKEQVMFM SDSVFTTRNLLEQIVLPLKKLTYIY SVVLTLVSEKVYDWKVLADVLGYSH LSLEDFDQIQADKESEKVSYVIKKL KEDCHTERNTRKFLYELIVALLKMD CQELVARLIQEAAVLTSAVKLGKGW RELAEKLVRLTKQQMEAYEIPHRGN TGDVAVEMMWKPAYDFLYTWSAHYG NNYRDVLQDLQSALDRMKNPVTKHW RELTGVLILVNSLEVLRVTAFSTSE EVTRTRPLEQKLISEEDLAANDILD YKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
