Recombinant Human MAD2L2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: MAD2L2-3376H
• Product Overview: MAD2L2 MS Standard C13 and N15-labeled recombinant protein (NP_001120797) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 24.3 kDa
• AA Sequence: MTTLTRQDLNFGQVVADVLCEFLEV AVHLILYVREVYPVGIFQKRKKYNV PVQMSCHPELNQYIQDTLHCVKPLL EKNDVEKVVVVILDKEHRPVEKFVF EITQPPLLSISSDSLLSHVEQLLRA FILKISVCDAVLDHNPPGCTFTVLV HTREAATRNMEKIQVIKDFPWILAD EQDVHMHDPRLIPLKTMTSDILKMQ LYVEERAHKGSTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MAD2L2 mitotic arrest deficient 2 like 2 [ Homo sapiens (human) ]
• Official Symbol: MAD2L2
• Synonyms: MAD2L2; MAD2 mitotic arrest deficient-like 2 (yeast); MAD2 (mitotic arrest deficient, yeast, homolog) like 2; mitotic spindle assembly checkpoint protein MAD2B; MAD2B; mitotic arrest deficient homolog like 2; REV7; hREV7; REV7 homolog; MAD2-like protein 2; mitotic arrest deficient homolog-like 2; mitotic arrest deficient 2-like protein 2; MAD2 (mitotic arrest deficient, yeast, homolog)-like 2
• Gene ID: 10459
• mRNA Refseq: NM_001127325
• Protein Refseq: NP_001120797
• MIM: 604094
• UniProt ID: Q9UI95