Recombinant Human MALT1, GST-tagged
Cat.No. : | MALT1-717H |
Product Overview : | Recombinant Human MALT1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 125-450aa |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 [ Homo sapiens ] |
Official Symbol : | MALT1 |
Synonyms : | MALT1; mucosa associated lymphoid tissue lymphoma translocation gene 1; MLT; mucosa-associated lymphoid tissue lymphoma translocation protein 1; paracaspase; caspase-like protein; MALT associated translocation; MALT lymphoma-associated translocation; MALT-lymphoma associated translocation; MLT1; DKFZp434L132; |
Gene ID : | 10892 |
mRNA Refseq : | NM_006785 |
Protein Refseq : | NP_006776 |
MIM : | 604860 |
UniProt ID : | Q9UDY8 |
Chromosome Location : | 18q21 |
Pathway : | Activation of NF-kappaB in B Cells, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem; BCR signaling pathway, organism-specific biosystem; Canonical NF-kappaB pathway, organism-specific biosystem; Downstream Signaling Events Of B Cell Receptor (BCR), organism-specific biosystem; |
Function : | cysteine-type endopeptidase activity; contributes_to kinase activator activity; peptidase activity; protein binding; protein self-association; signal transducer activity; ubiquitin-protein ligase activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMALT1 inhibitors are being investigated to prevent graft rejection and reduce the need for immunosuppressive drugs in transplant recipients.
Some genetic variations in MALT1 may influence susceptibility to certain diseases, including autoimmune conditions.
Yes, MALT1 is implicated in lymphoma and other hematological malignancies, making it a potential therapeutic target.
Yes, researchers are exploring MALT1 inhibitors as potential cancer therapeutics to block its activity in lymphomas.
MALT1 is involved in the activation of T and B cells, which are essential for the adaptive immune response.
Customer Reviews (3)
Write a reviewFrom recombinant protein production to modification or labeling services, the company is committed to assisting researchers in obtaining the MALT1 protein in the format and specifications required for their particular studies.
the manufacturer understands the importance of customization and can offer tailored solutions to meet specific research needs.
the MALT1 protein's exceptional qualities, combined with the manufacturer's comprehensive technical support, make it an ideal choice for researchers seeking reliable experimental materials and reliable assistance in their scientific endeavors.
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