Recombinant Human MAOA Protein, Full Length, N-FLAG tagged

• Cat.No.: MAOA-11H
• Product Overview: Recombinant MAOA (accession number NP_000231.1) was expressed in Sf9 cells and contains an N-terminal FLAG-Tag.

Specification

• Description: This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
• Source: Insect cells
• Species: Human
• Tag: N-FLAG
• Protein length: Full Length
• Molecular Mass: 60.7 kDa
• Purity: > 80% pure by SDS-PAGE
• Applications: Recombinant MAOA is suitable for use in the study of enzyme kinetics, inhibitor screening, and selectivity profiling.
  Monoamine Oxidase Assay: 40 μM substrate was incubated with MAOA protein in reaction buffer for 1 hour at room temperature, then the product was incubated with Detection Reagent for 0.5 hour at temperature. The activity of MAOA was detected by Promega MAO-Glo Assay.
• Storage: Recombinant proteins in solution are temperature sensitive and must be stored at -80 centigrade to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
• GeneID: 4128

Gene Information

• Gene Name: MAOA monoamine oxidase A [ Homo sapiens (human) ]
• Official Symbol: MAOA
• Synonyms: MAOA; monoamine oxidase A; BRNRS; MAO-A; amine oxidase [flavin-containing] A; monoamine oxidase type A; EC 1.4.3.21; EC 1.4.3.4
• mRNA Refseq: NM_000240
• Protein Refseq: NP_000231
• MIM: 309850
• UniProt ID: P21397