Recombinant Human MAP3K1 protein, His & T7-tagged
Cat.No. : | MAP3K1-1540H |
Product Overview : | Recombinant Human MAP3K1 aa. (Ile1307~Arg1509 (Accession # Q13233)) fused with N-terminal His & T7 tag was produced in E. coli cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. |
Source : | E. coli |
Species : | Human |
Tag : | His & T7 |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 26.1kDa. |
Protein length : | Ile1307~Arg1509 (Accession # Q13233) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method). |
Purity : | >95% |
Characteristic : | The isoelectric point is 9.2. |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | MAP3K1 mitogen-activated protein kinase kinase kinase 1 [ Homo sapiens (human) ] |
Official Symbol : | MAP3K1 |
Synonyms : | MEKK; MEKK1; SRXY6; MEKK 1; MAPKKK1; MAP/ERK kinase kinase 1; MAPK/ERK kinase kinase 1; MEK kinase 1; mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase; mitogen-activated protein kinase kinase kinase 1 |
Gene ID : | 4214 |
mRNA Refseq : | NM_005921.1 |
Protein Refseq : | NP_005912.1 |
UniProt ID : | Q13233 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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