Recombinant Human MCL1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: MCL1-5820H
• Product Overview: MCL1 MS Standard C13 and N15-labeled recombinant protein (NP_068779) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 37.2 kDa
• AA Sequence: MFGLKRNAVIGLNLYCGGAGLGAGS GGATRPGGRLLATEKEASARREIGG GEAGAVIGGSAGASPPSTLTPDSRR VARPPPIGAEVPDVTATPARLLFFA PTRRAAPLEEMEAPAADAIMSPEEE LDGYEPEPLGKRPAVLPLLELVGES GNNTSTDGSLPSTPPPAEEEEDELY RQSLEIISRYLREQATGAKDTKPMG RSGATSRKALETLRRVGDGVQRNHE TAFQGMLRKLDIKNEDDVKSLSRVM IHVFSDGVTNWGRIVTLISFGAFVA KHLKTINQESCIEPLAESITDVLVR TKRDWLVKQRGWDGFVEFFHVEDLE GGIRNVLLAFAGVAGVGAGLAYLIR TRTRPLEQKLISEEDLAANDILDYK DDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MCL1 MCL1 apoptosis regulator, BCL2 family member [ Homo sapiens (human) ]
• Official Symbol: MCL1
• Synonyms: MCL1; myeloid cell leukemia sequence 1 (BCL2-related); induced myeloid leukemia cell differentiation protein Mcl-1; BCL2L3; Mcl 1; bcl-2-like protein 3; myeloid cell leukemia ES; bcl-2-related protein EAT/mcl1; TM; EAT; MCL1L; MCL1S; Mcl-1; MCL1-ES; bcl2-L-3; mcl1/EAT; MGC1839; MGC104264
• Gene ID: 4170
• mRNA Refseq: NM_021960
• Protein Refseq: NP_068779
• MIM: 159552
• UniProt ID: Q07820