Recombinant Human MEF2D protein, MYC/DDK-tagged
Cat.No. : | MEF2D-818H |
Product Overview : | Recombinant Human MEF2D fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 55.8 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Notes : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | MEF2D myocyte enhancer factor 2D [ Homo sapiens ] |
Official Symbol : | MEF2D |
Synonyms : | MEF2D; myocyte enhancer factor 2D; myocyte-specific enhancer factor 2D; MEF2D/DAZAP1 fusion; MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D); myocyte enhancer factor 2D/deleted in azoospermia associated protein 1 fusion protein; DKFZp686I1536; |
Gene ID : | 4209 |
mRNA Refseq : | NM_005920 |
Protein Refseq : | NP_005911 |
MIM : | 600663 |
UniProt ID : | Q14814 |
Chromosome Location : | 1q12-q23 |
Pathway : | Adipogenesis, organism-specific biosystem; CDO in myogenesis, organism-specific biosystem; Circadian Clock, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Energy Metabolism, organism-specific biosystem; Myogenesis, organism-specific biosystem; Role of Calcineurin-dependent NFAT signaling in lymphocytes, organism-specific biosystem; |
Function : | DNA binding; RNA polymerase II regulatory region sequence-specific DNA binding; activating transcription factor binding; histone deacetylase binding; protein binding; protein dimerization activity; protein heterodimerization activity; protein homodimerization activity; sequence-specific DNA binding RNA polymerase II transcription factor activity; sequence-specific DNA binding transcription factor activity; |
Products Types
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MEF2D-1394H | Recombinant Human MEF2D Protein, His (Fc)-Avi-tagged | +Inquiry |
MEF2D-308H | Recombinant Human MEF2D Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
MEF2D-820H | Recombinant Human MEF2D protein, GST-tagged | +Inquiry |
◆ Lysates | ||
MEF2D-4374HCL | Recombinant Human MEF2D 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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