Recombinant Human Methylmalonyl CoA Epimerase, His-tagged
Cat.No. : | MCEE-801H |
Product Overview : | Recombinant human MCEE protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW = 17.3 kDa (161aa) confirmed by MALDI-TOF. |
- Specification
- Gene Information
- Related Products
Cat. No. : | MCEE-801H |
Description : | MCEE catalyzes the interconversion of D- and L-methylmalonyl-CoA during the degradation of branched chain amino acids, odd chain-length fatty acids, and other metabolites. This protein deficiency is an autosomal recessive inborn error of amino acid metabolism, involving valine, threonine, isoleucine and methionine. This organic aciduria may present in the neonatal period with life-threatening metabolic acidosis, hyperammonemia, feeding difficulties, pancytopenia and coma. |
Source : | E.coli. |
Sequences Of Amino Acids : | MGSSHHHHHH SSGLVPRGSH MQVTGSVWNL GRLNHVAIAV PDLEKAAAFY KNILGAQVSE AVPLPEHGVS VVFVNLGNTK MELLHPLGRD SPIAGFLQKN KAGGMHHICI EVDNINAAVM DLKKKKIRSL SEEVKIGAHG KPVIFLHPKD CGGVLVELEQ A |
Purity : | > 90% by SDS – PAGE. |
Form : | Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 1mM DTT, 0.1mM PMSF, 10% glycerol. |
Concentration : | 1 mg/ml (determined by Bradford assay). |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Gene Name : | MCEE methylmalonyl CoA epimerase [ Homo sapiens ] |
Synonyms : | MCEE; methylmalonyl CoA epimerase; GLOD2; methylmalonyl-CoA epimerase, mitochondrial; DL-methylmalonyl-CoA racemase; glyoxalase domain containing 2; EC 5.1.99.1 |
Gene ID : | 84693 |
mRNA Refseq : | NM_032601 |
Protein Refseq : | NP_115990 |
MIM : | 608419 |
UniProt ID : | Q96PE7 |
Chromosome Location : | 2p13.3 |
Pathway : | Metabolic pathways; Propanoate metabolism; Valine, leucine and isoleucine degradation |
Function : | isomerase activity; methylmalonyl-CoA epimerase activity |
Products Types
◆ Recombinant Protein | ||
MCEE-5406M | Recombinant Mouse MCEE Protein, His (Fc)-Avi-tagged | +Inquiry |
MCEE-5210H | Recombinant Human MCEE Protein (Gln37-Ala176), C-His tagged | +Inquiry |
MCEE-5551C | Recombinant Chicken MCEE | +Inquiry |
MCEE-9626M | Recombinant Mouse MCEE Protein | +Inquiry |
Mcee-1735R | Recombinant Rat Mcee protein, His & T7-tagged | +Inquiry |
◆ Lysates | ||
MCEE-4426HCL | Recombinant Human MCEE 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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