Recombinant Human METTL3 Protein, His-tagged

• Cat.No.: METTL3-12H
• Product Overview: Recombinant human METTL3 protein (2-580) with a N-terminal His-tag and recombinant human METTL14(2-456) protein with a N-terminal GST/His-tag were expressed in insect cells.

Specification

• Description: This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
• Source: Insect cell
• Species: Human
• Tag: His
• Form: 10 mM Tris, with 500 mM sodium chloride, 1 mM DTT, and 5% glycerol
• Molecular Mass: 66.3 kDa
• Protein length: 2-580
• Purity: ≥80% estimated by SDS-PAGE
• Applications: WB, ELISA
• Stability: ≥ 1 year
• Storage: Store at -80 centigrade

Gene Information

• Gene Name: METTL3 methyltransferase like 3 [ Homo sapiens (human) ]
• Official Symbol: METTL3
• Synonyms: METTL3; methyltransferase like 3; M6A; IME4; Spo8; MT-A70; hMETTL3; N6-adenosine-methyltransferase catalytic subunit; N6-adenosine-methyltransferase 70 kDa subunit; adoMet-binding subunit of the human mRNA (N6-adenosine)-methyltransferase; mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase; mRNA m(6)A methyltransferase; methyltransferase-like protein 3
• Gene ID: 56339
• mRNA Refseq: NM_019852
• Protein Refseq: NP_062826
• MIM: 612472
• UniProt ID: Q86U44