Recombinant Human MICAL2 Protein (1-495 aa), His-tagged
Cat.No. : | MICAL2-1455H |
Product Overview : | Recombinant Human MICAL2 Protein (1-495 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Cell Biology. Protein Description: Partial. |
- Specification
- Gene Information
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Description : | Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin and regulates the SRF signaling. Acts by modifying nuclear actin subunits through the addition of oxygen to form methionine-sulfoxide, leading to promote actin filament severing and prevent repolymerization. Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA. |
Source : | Yeast |
Species : | Human |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 58.5 kDa |
Protein length : | 1-495 aa |
AA Sequence : | MGENEDEKQAQAGQVFENFVQASTC KGTLQAFNILTRHLDLDPLDHRNFY SKLKSKVTTWKAKALWYKLDKRGSH KEYKRGKSCTNTKCLIVGGGPCGLR TAIELAYLGAKVVVVEKRDSFSRNN VLHLWPFTIHDLRGLGAKKFYGKFC AGSIDHISIRQLQLILFKVALMLGV EIHVNVEFVKVLEPPEDQENQKIGW RAEFLPTDHSLSEFEFDVIIGADGR RNTLEGFRRKEFRGKLAIAITANFI NRNSTAEAKVEEISGVAFIFNQKFF QDLKEETGIDLENIVYYKDCTHYFV MTAKKQSLLDKGVIINDYIDTEMLL CAENVNQDNLLSYAREAADFATNYQ LPSLDFAMNHYGQPDVAMFDFTCMY ASENAALVRERQAHQLLVALVGDSL LEPFWPMGTGCARGFLAAFDTAWMV KSWNQGTPPLELLAERESLYRLLPQ TTPENINKNFEQYTLDPGTRYPNLN SHCVRPHQVKHLYITKELEH |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
Gene Name : | MICAL2 microtubule associated monoxygenase, calponin and LIM domain containing 2 [ Homo sapiens ] |
Official Symbol : | MICAL2 |
Synonyms : | MICAL2; KIAA0750; MICAL-2; MICAL2PV1; MICAL2PV2; DKFZp686H2469; DKFZp686H03148; |
Gene ID : | 9645 |
mRNA Refseq : | NM_014632 |
Protein Refseq : | NP_055447 |
MIM : | 608881 |
UniProt ID : | O94851 |
Products Types
◆ Recombinant Protein | ||
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MICAL2-5550M | Recombinant Mouse MICAL2 Protein, His (Fc)-Avi-tagged | +Inquiry |
MICAL2-9827M | Recombinant Mouse MICAL2 Protein | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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